Characterisation and confirmation of rare beta-thalassaemia mutations in the Malay, Chinese and Indian ethnic groups in Malaysia

In Malaysia, about 4.5% of the Malay and Chinese populations are heterozygous carriers of β-thalassaemia. The initial identification of rare β-globin gene mutations by genomic sequencing will allow the development of simpler and cost-effective PCR-based techniques to complement the existing amplific...

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