The Benzodiazepine Alprazolam Dissociates Contextual Fear from Cued Fear in Humans as Assessed by Fear-potentiated Startle

The startle reflex is potentiated by aversive states. It has been proposed that phasic startle potentiation to a threat cue and sustained startle potentiation to contextual stimuli reflect distinct processes mediated by different brain structures. The present study tested the hypothesis that alprazo...

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Veröffentlicht in:	Biological psychiatry (1969) 2006-10, Vol.60 (7), p.760-766
Hauptverfasser:	Grillon, Christian, Baas, Johanna M.P., Pine, Daniel S., Lissek, Shmuel, Lawley, Megan, Ellis, Valerie, Levine, Jessica
Format:	Artikel
Sprache:	eng
Schlagworte:	Acoustic Stimulation Adult Alprazolam Alprazolam - pharmacology Analysis of Variance Anti-Anxiety Agents - pharmacology anxiety Anxiety - psychology Association Learning - drug effects benzodiazepine Biological and medical sciences Conditioning, Classical - drug effects context Cross-Over Studies Diphenhydramine - pharmacology Dose-Response Relationship, Drug Double-Blind Method Environment fear Fear - drug effects Fear - psychology Female Humans Hypnotics and Sedatives - pharmacology Male Medical sciences Neuropharmacology Pharmacology. Drug treatments Psycholeptics: tranquillizer, neuroleptic Psychology. Psychoanalysis. Psychiatry Psychopharmacology Reference Values Reflex, Startle - drug effects startle reflex
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