Influence of ultraviolet radiation on the production of 25 hydroxyvitamin d in the elderly population in the city of São Paulo (23 ° 34's), Brazil
The lack of vitamin D is a major changeable factor involved in the pathophysiology of osteoporosis. Since the major source for this hormone is its cutaneous synthesis via ultraviolet radiation (UVR), we studied the serum level of 25-hydroxyvitamin D (25OHD) in 250 free-living elderly people (79.1 ye...
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| Veröffentlicht in: | Osteoporosis international 2005-12, Vol.16 (12), p.1649-1654 |
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| creator | LUPORINI SARAIVA, Gabriela SEABRA CENDOROGLO, Maysa RAMOS, Luiz Roberto QUIRINO, Lara Miguel VIEIRA, Araujo José Gilberto H KUNII, Ilda HAYASHI, Lillian F CORREA, Marcelode Paula LAZARETTI-CASTRO, Marise |
| description | The lack of vitamin D is a major changeable factor involved in the pathophysiology of osteoporosis. Since the major source for this hormone is its cutaneous synthesis via ultraviolet radiation (UVR), we studied the serum level of 25-hydroxyvitamin D (25OHD) in 250 free-living elderly people (79.1 years old) from a subtropical region according to the UVR incidence and its correlations with parathormone (PTH) and ionized calcium. UVR and 25OHD differed according to the season of the year (P |
| doi_str_mv | 10.1007/s00198-005-1895-3 |
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Since the major source for this hormone is its cutaneous synthesis via ultraviolet radiation (UVR), we studied the serum level of 25-hydroxyvitamin D (25OHD) in 250 free-living elderly people (79.1 years old) from a subtropical region according to the UVR incidence and its correlations with parathormone (PTH) and ionized calcium. UVR and 25OHD differed according to the season of the year (P<0.001), with greater radiation in the summer and less in the winter, whereas the 25OHD peak and nadir occurred in autumn and spring, respectively. The highest 25OHD mean was 67.2 nmol/l, and the lowest was 29.1 nmol/l corresponding, respectively, to the measure of the month subsequent to the one of most and least sunlight incidence. Clustered by season, the correlation between UVR and 25OHD for the following seasons was r=0.98 and between the PTH and 25OHD of corresponding seasons, r=-0.95. Vitamin D deficiency occurred in 15.4% of patients, insufficiency in 41.9% and secondary hyperparathyroidism in 55%. In conclusion, we found a seasonal variation in 25OHD levels that strongly correlated with the PTH levels when separated by the seasons of the year. The 25OHD levels correlated with the UVR of the previous quarter, requiring no less than 30 days for serum changes arising from exposure to or deprivation of UVR to be observed. The prevalence of vitamin D deficiency/insufficiency found was greater than expected, even when compared to countries exposed to less solar irradiation. Thus, measures to encourage greater sun exposure and food enrichment policies should also be considered.</description><identifier>ISSN: 0937-941X</identifier><identifier>EISSN: 1433-2965</identifier><identifier>DOI: 10.1007/s00198-005-1895-3</identifier><identifier>PMID: 15947862</identifier><language>eng</language><publisher>London: Springer</publisher><subject>Aged ; Biological and medical sciences ; Brazil - epidemiology ; Calcium - blood ; Climate ; Cross-Sectional Studies ; Diseases of the osteoarticular system ; Exercise ; Female ; Fractures ; Humans ; Life Style ; Male ; Medical sciences ; Older people ; Osteoporosis ; Osteoporosis. Osteomalacia. Paget disease ; Parathyroid Hormone - blood ; Pathophysiology ; Patients ; Prevalence ; Seasons ; Sex Distribution ; Sunlight ; Ultraviolet radiation ; Ultraviolet Rays ; Vitamin D ; Vitamin D - analogs & derivatives ; Vitamin D - biosynthesis ; Vitamin D - blood ; Vitamin D Deficiency - blood ; Vitamin D Deficiency - epidemiology ; Vitamin D Deficiency - ethnology</subject><ispartof>Osteoporosis international, 2005-12, Vol.16 (12), p.1649-1654</ispartof><rights>2006 INIST-CNRS</rights><rights>International Osteoporosis Foundation and National Osteoporosis Foundation 2005</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c422t-c4775be91521763c7beec41376ec70128915f87e1fcd70aa7f41f5f162b0d9153</citedby><cites>FETCH-LOGICAL-c422t-c4775be91521763c7beec41376ec70128915f87e1fcd70aa7f41f5f162b0d9153</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,782,786,27931,27932</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17355034$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15947862$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>LUPORINI SARAIVA, Gabriela</creatorcontrib><creatorcontrib>SEABRA CENDOROGLO, Maysa</creatorcontrib><creatorcontrib>RAMOS, Luiz Roberto</creatorcontrib><creatorcontrib>QUIRINO, Lara Miguel</creatorcontrib><creatorcontrib>VIEIRA, Araujo José Gilberto H</creatorcontrib><creatorcontrib>KUNII, Ilda</creatorcontrib><creatorcontrib>HAYASHI, Lillian F</creatorcontrib><creatorcontrib>CORREA, Marcelode Paula</creatorcontrib><creatorcontrib>LAZARETTI-CASTRO, Marise</creatorcontrib><title>Influence of ultraviolet radiation on the production of 25 hydroxyvitamin d in the elderly population in the city of São Paulo (23 ° 34's), Brazil</title><title>Osteoporosis international</title><addtitle>Osteoporos Int</addtitle><description>The lack of vitamin D is a major changeable factor involved in the pathophysiology of osteoporosis. Since the major source for this hormone is its cutaneous synthesis via ultraviolet radiation (UVR), we studied the serum level of 25-hydroxyvitamin D (25OHD) in 250 free-living elderly people (79.1 years old) from a subtropical region according to the UVR incidence and its correlations with parathormone (PTH) and ionized calcium. UVR and 25OHD differed according to the season of the year (P<0.001), with greater radiation in the summer and less in the winter, whereas the 25OHD peak and nadir occurred in autumn and spring, respectively. The highest 25OHD mean was 67.2 nmol/l, and the lowest was 29.1 nmol/l corresponding, respectively, to the measure of the month subsequent to the one of most and least sunlight incidence. Clustered by season, the correlation between UVR and 25OHD for the following seasons was r=0.98 and between the PTH and 25OHD of corresponding seasons, r=-0.95. Vitamin D deficiency occurred in 15.4% of patients, insufficiency in 41.9% and secondary hyperparathyroidism in 55%. In conclusion, we found a seasonal variation in 25OHD levels that strongly correlated with the PTH levels when separated by the seasons of the year. The 25OHD levels correlated with the UVR of the previous quarter, requiring no less than 30 days for serum changes arising from exposure to or deprivation of UVR to be observed. The prevalence of vitamin D deficiency/insufficiency found was greater than expected, even when compared to countries exposed to less solar irradiation. Thus, measures to encourage greater sun exposure and food enrichment policies should also be considered.</description><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Brazil - epidemiology</subject><subject>Calcium - blood</subject><subject>Climate</subject><subject>Cross-Sectional Studies</subject><subject>Diseases of the osteoarticular system</subject><subject>Exercise</subject><subject>Female</subject><subject>Fractures</subject><subject>Humans</subject><subject>Life Style</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Older people</subject><subject>Osteoporosis</subject><subject>Osteoporosis. Osteomalacia. Paget disease</subject><subject>Parathyroid Hormone - blood</subject><subject>Pathophysiology</subject><subject>Patients</subject><subject>Prevalence</subject><subject>Seasons</subject><subject>Sex Distribution</subject><subject>Sunlight</subject><subject>Ultraviolet radiation</subject><subject>Ultraviolet Rays</subject><subject>Vitamin D</subject><subject>Vitamin D - analogs & derivatives</subject><subject>Vitamin D - biosynthesis</subject><subject>Vitamin D - blood</subject><subject>Vitamin D Deficiency - blood</subject><subject>Vitamin D Deficiency - epidemiology</subject><subject>Vitamin D Deficiency - ethnology</subject><issn>0937-941X</issn><issn>1433-2965</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNpdkVuKFDEYhYMoTs_oAnyRIHgDS3OtJI_O4GVgQEEF30I6lTAZ0pU2qQyW63AHbsA16MZMUwUDQvgDOd855OcA8ACjlxgh8aoghJXsEOIdlop39BbYYEZpR1TPb4MNUlR0iuGvR-C4lCvUPEqJu-AIc8WE7MkG_DwffaxutA4mD2ucsrkOKboJZjMEM4U0wnamSwf3OQ3VLi8eEg4v5yGn7_N1mMwujHCAYQFdHFyOM9ynfY1LxKrYMM0H86e_vxL8aGpM8Bmh8M9vSNnT8vwFPM3mR4j3wB1vYnH31_sEfHn75vPZ--7iw7vzs9cXnWWETG0KwbdOYU6w6KkVW-csw1T0zgqEiWyKl8JhbweBjBGeYc897skWDU2jJ-DJkttW-1ZdmfQuFOtiNKNLteheKkQ5Rg189B94lWoe2980wVJSwSRrEF4gm1Mp2Xm9z2Fn8qwx0oe-9NKXbn3pQ1-aNs_DNbhud264cawFNeDxCphiTfTZjDaUG05QzhFl9B98eJ4O</recordid><startdate>20051201</startdate><enddate>20051201</enddate><creator>LUPORINI SARAIVA, Gabriela</creator><creator>SEABRA CENDOROGLO, Maysa</creator><creator>RAMOS, Luiz Roberto</creator><creator>QUIRINO, Lara Miguel</creator><creator>VIEIRA, Araujo José Gilberto H</creator><creator>KUNII, Ilda</creator><creator>HAYASHI, Lillian F</creator><creator>CORREA, Marcelode Paula</creator><creator>LAZARETTI-CASTRO, Marise</creator><general>Springer</general><general>Springer Nature B.V</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7RV</scope><scope>7TS</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20051201</creationdate><title>Influence of ultraviolet radiation on the production of 25 hydroxyvitamin d in the elderly population in the city of São Paulo (23 ° 34's), Brazil</title><author>LUPORINI SARAIVA, Gabriela ; SEABRA CENDOROGLO, Maysa ; RAMOS, Luiz Roberto ; QUIRINO, Lara Miguel ; VIEIRA, Araujo José Gilberto H ; KUNII, Ilda ; HAYASHI, Lillian F ; CORREA, Marcelode Paula ; LAZARETTI-CASTRO, Marise</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c422t-c4775be91521763c7beec41376ec70128915f87e1fcd70aa7f41f5f162b0d9153</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Brazil - epidemiology</topic><topic>Calcium - blood</topic><topic>Climate</topic><topic>Cross-Sectional Studies</topic><topic>Diseases of the osteoarticular system</topic><topic>Exercise</topic><topic>Female</topic><topic>Fractures</topic><topic>Humans</topic><topic>Life Style</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Older people</topic><topic>Osteoporosis</topic><topic>Osteoporosis. 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Paget disease</topic><topic>Parathyroid Hormone - blood</topic><topic>Pathophysiology</topic><topic>Patients</topic><topic>Prevalence</topic><topic>Seasons</topic><topic>Sex Distribution</topic><topic>Sunlight</topic><topic>Ultraviolet radiation</topic><topic>Ultraviolet Rays</topic><topic>Vitamin D</topic><topic>Vitamin D - analogs & derivatives</topic><topic>Vitamin D - biosynthesis</topic><topic>Vitamin D - blood</topic><topic>Vitamin D Deficiency - blood</topic><topic>Vitamin D Deficiency - epidemiology</topic><topic>Vitamin D Deficiency - ethnology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>LUPORINI SARAIVA, Gabriela</creatorcontrib><creatorcontrib>SEABRA CENDOROGLO, Maysa</creatorcontrib><creatorcontrib>RAMOS, Luiz Roberto</creatorcontrib><creatorcontrib>QUIRINO, Lara Miguel</creatorcontrib><creatorcontrib>VIEIRA, Araujo José Gilberto H</creatorcontrib><creatorcontrib>KUNII, Ilda</creatorcontrib><creatorcontrib>HAYASHI, Lillian F</creatorcontrib><creatorcontrib>CORREA, Marcelode Paula</creatorcontrib><creatorcontrib>LAZARETTI-CASTRO, Marise</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Physical Education Index</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Osteoporosis international</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>LUPORINI SARAIVA, Gabriela</au><au>SEABRA CENDOROGLO, Maysa</au><au>RAMOS, Luiz Roberto</au><au>QUIRINO, Lara Miguel</au><au>VIEIRA, Araujo José Gilberto H</au><au>KUNII, Ilda</au><au>HAYASHI, Lillian F</au><au>CORREA, Marcelode Paula</au><au>LAZARETTI-CASTRO, Marise</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Influence of ultraviolet radiation on the production of 25 hydroxyvitamin d in the elderly population in the city of São Paulo (23 ° 34's), Brazil</atitle><jtitle>Osteoporosis international</jtitle><addtitle>Osteoporos Int</addtitle><date>2005-12-01</date><risdate>2005</risdate><volume>16</volume><issue>12</issue><spage>1649</spage><epage>1654</epage><pages>1649-1654</pages><issn>0937-941X</issn><eissn>1433-2965</eissn><abstract>The lack of vitamin D is a major changeable factor involved in the pathophysiology of osteoporosis. Since the major source for this hormone is its cutaneous synthesis via ultraviolet radiation (UVR), we studied the serum level of 25-hydroxyvitamin D (25OHD) in 250 free-living elderly people (79.1 years old) from a subtropical region according to the UVR incidence and its correlations with parathormone (PTH) and ionized calcium. UVR and 25OHD differed according to the season of the year (P<0.001), with greater radiation in the summer and less in the winter, whereas the 25OHD peak and nadir occurred in autumn and spring, respectively. The highest 25OHD mean was 67.2 nmol/l, and the lowest was 29.1 nmol/l corresponding, respectively, to the measure of the month subsequent to the one of most and least sunlight incidence. Clustered by season, the correlation between UVR and 25OHD for the following seasons was r=0.98 and between the PTH and 25OHD of corresponding seasons, r=-0.95. Vitamin D deficiency occurred in 15.4% of patients, insufficiency in 41.9% and secondary hyperparathyroidism in 55%. In conclusion, we found a seasonal variation in 25OHD levels that strongly correlated with the PTH levels when separated by the seasons of the year. The 25OHD levels correlated with the UVR of the previous quarter, requiring no less than 30 days for serum changes arising from exposure to or deprivation of UVR to be observed. The prevalence of vitamin D deficiency/insufficiency found was greater than expected, even when compared to countries exposed to less solar irradiation. Thus, measures to encourage greater sun exposure and food enrichment policies should also be considered.</abstract><cop>London</cop><pub>Springer</pub><pmid>15947862</pmid><doi>10.1007/s00198-005-1895-3</doi><tpages>6</tpages></addata></record> |
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| subjects | Aged Biological and medical sciences Brazil - epidemiology Calcium - blood Climate Cross-Sectional Studies Diseases of the osteoarticular system Exercise Female Fractures Humans Life Style Male Medical sciences Older people Osteoporosis Osteoporosis. Osteomalacia. Paget disease Parathyroid Hormone - blood Pathophysiology Patients Prevalence Seasons Sex Distribution Sunlight Ultraviolet radiation Ultraviolet Rays Vitamin D Vitamin D - analogs & derivatives Vitamin D - biosynthesis Vitamin D - blood Vitamin D Deficiency - blood Vitamin D Deficiency - epidemiology Vitamin D Deficiency - ethnology |
| title | Influence of ultraviolet radiation on the production of 25 hydroxyvitamin d in the elderly population in the city of São Paulo (23 ° 34's), Brazil |
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