The Neural Correlates of Anhedonia in Major Depressive Disorder

Anhedonia is a relative lack of pleasure in response to formerly rewarding stimuli. It is an important diagnostic feature of major depressive disorder (MDD), and predicts antidepressant efficacy. Understanding its neurobiological basis may help to target new treatments and predict treatment outcomes...

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Veröffentlicht in:	Biological psychiatry (1969) 2005-12, Vol.58 (11), p.843-853
Hauptverfasser:	Keedwell, Paul A., Andrew, Chris, Williams, Steven C.R., Brammer, Mick J., Phillips, Mary L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adult and adolescent clinical studies Affect - physiology Anxiety - physiopathology Biological and medical sciences Brain Mapping Depression Depressive Disorder, Major - pathology Depressive Disorder, Major - psychology Echo-Planar Imaging Female fMRI Happiness Humans Magnetic Resonance Imaging Major depression Male Medical sciences Memory Middle Aged Mood disorders mood induction Neostriatum - pathology prefrontal cortex Psychiatric Status Rating Scales Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Reward striatum
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