Brief Report: Enzyme Inducers Reduce Elimination Half-Life After a Single Dose of Nevirapine in Healthy Women

OBJECTIVE:Single-dose nevirapine (SD-NVP) to prevent mother-to-child transmission (MTCT) of HIV is associated with development of NVP resistance, probably because of its long half-life in combination with a low genetic barrier to resistance. The objective of this study was to find enzyme inducers to...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of acquired immune deficiency syndromes (1999) 2006-10, Vol.43 (2), p.193-196
Hauptverfasser:	Lʼhomme, Rafaëlla F. A, Dijkema, Tim, van der Ven, Andre J. A. M, Burger, David M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult AIDS/HIV Clinical trials Drug Resistance, Viral Drug therapy Enzyme Induction - drug effects Enzymes Female Half-Life HIV Human immunodeficiency virus Humans Nevirapine - pharmacokinetics Nevirapine - pharmacology Pilot Projects Womens health
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!