Spontaneous Liver Hemorrhage During Laparotomy for Necrotizing Enterocolitis: A Potential Role for Recombinant Factor VIIa

Necrotizing enterocolitis remains a serious condition in very low birth weight infants, particularly in those infants who require surgery. Perioperative hemorrhage is a potentially fatal complication in this population. We describe our experience in 4 premature infants with necrotizing enterocolitis...

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Veröffentlicht in:	The Journal of pediatrics 2005-12, Vol.147 (6), p.857-859
Hauptverfasser:	Filan, Peter M., Mills, John F., Clarnette, Tom D., Ekert, Henry, Ekert, Paul
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Enterocolitis, Necrotizing - surgery Factor VIIa - therapeutic use Gastroenterology. Liver. Pancreas. Abdomen General aspects Hemorrhage - drug therapy Humans Infant Infant, Newborn Infant, Premature Infant, Very Low Birth Weight Intraoperative Complications - drug therapy Laparotomy Liver Diseases - drug therapy Medical sciences Other diseases. Semiology Recombinant Proteins - therapeutic use Rupture, Spontaneous Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Treatment Outcome
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Zusammenfassung:	Necrotizing enterocolitis remains a serious condition in very low birth weight infants, particularly in those infants who require surgery. Perioperative hemorrhage is a potentially fatal complication in this population. We describe our experience in 4 premature infants with necrotizing enterocolitis who received recombinant factor VIIa to manage life-threatening intraoperative hemorrhage.
ISSN:	0022-3476 1097-6833
DOI:	10.1016/j.jpeds.2005.07.034