Decrease of cytotoxic T cells in allergic asthma correlates with total serum immunglobulin E

Background: Allergic asthma has been linked to an increase in T‐helper type 2‐like cytokines and T cells, but there is growing evidence for a role of lymphocyte‐mediated cytotoxic mechanisms in the pathogenesis of asthma. Therefore, we investigated the cytotoxic potential of different lymphocyte su...

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Veröffentlicht in:	Allergy 2006-11, Vol.61 (11), p.1351-1357
Hauptverfasser:	Bratke, K., Haupt, F., Kuepper, M., Bade, B., Faehndrich, S., Luttmann, W., Virchow, J. C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Allergic diseases apoptosis Asthma - immunology atopy Biological and medical sciences cytotoxic lymphocyte Female Fundamental and applied biological sciences. Psychology Fundamental immunology granzyme Granzymes - analysis Granzymes - blood Humans Immunoglobulin E - blood Immunopathology Interleukin-4 - blood Male Medical sciences Membrane Glycoproteins - analysis Perforin Pore Forming Cytotoxic Proteins - analysis Respiratory Hypersensitivity - immunology T-Lymphocyte Subsets - enzymology T-Lymphocyte Subsets - immunology T-Lymphocytes, Cytotoxic - enzymology T-Lymphocytes, Cytotoxic - immunology
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