Laser-Fluoride Effect on Root Demineralization
Although the individual cariostatic effects of laser and fluoride have been shown, the combined effect of CO2 laser and fluoride on root demineralization remains uncertain and was the main aim of this study. By using a pH-cycling system and Polarized Light Microscopy, we demonstrated the synergistic...
Gespeichert in:
| Veröffentlicht in: | Journal of dental research 2006-10, Vol.85 (10), p.919-923 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 923 |
|---|---|
| container_issue | 10 |
| container_start_page | 919 |
| container_title | Journal of dental research |
| container_volume | 85 |
| creator | Gao, X.-L. Pan, J.-S. Hsu, C.-Y. |
| description | Although the individual cariostatic effects of laser and fluoride have been shown, the combined effect of CO2 laser and fluoride on root demineralization remains uncertain and was the main aim of this study. By using a pH-cycling system and Polarized Light Microscopy, we demonstrated the synergistic effect of fluoride combined with CO2 laser treatment on reducing root demineralization. The mean lesion depths (in μm) for each group were 160 ± 14 (Control), 113 ± 8 (Laser treatment alone), 111 ± 6 (Fluoride treatment alone), and 25 ± 7 (Fluoride followed by laser treatment). A significant laser-enhanced fluoride uptake, characterized by the ToF-SIMS analysis, was revealed by the 37% and 400% increments in loosely and firmly bound fluorides (both p < 0.002) in laser-irradiated areas, compared with the non-irradiated controls. In conclusion, there is a significant synergistic effect of combined CO2 laser and fluoride treatment on the inhibition of root demineralization, possibly due to laser-enhanced fluoride uptake in the root. |
| doi_str_mv | 10.1177/154405910608501009 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_68888051</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sage_id>10.1177_154405910608501009</sage_id><sourcerecordid>19384114</sourcerecordid><originalsourceid>FETCH-LOGICAL-c494t-cc24a0bcce4a2e4be89bb2422e6471b603dd71e4fe60a5459724c51b65fc33293</originalsourceid><addsrcrecordid>eNqFkEFLw0AQhRdRbK3-AQ9SPHhLO7s7m2SPUlsVCoLoOWw2E0lJsnU3OeivN6UFQUHnMjDzvTfMY-ySw4zzJJlzhQhKc4ghVcAB9BEb74bRbnrMxgBCRCBRjdhZCBsArkUqT9mIx1qnXIoxm61NIB-t6t75qqDpsizJdlPXTp-d66Z31FQteVNXn6arXHvOTkpTB7o49Al7XS1fFg_R-un-cXG7jixq7CJrBRrIrSU0gjCnVOe5QCEoxoTnMciiSDhhSTEYhUonAq0aFqq0UgotJ-xm77v17r2n0GVNFSzVtWnJ9SGL06FA8X9BrmWKnOMAXv8AN6737fBEJkCjEjGKARJ7yHoXgqcy2_qqMf4j45DtMs9-Zz6Irg7Ofd5Q8S05hDwA8z0QzBt9n_3D8guCZIay</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>209452642</pqid></control><display><type>article</type><title>Laser-Fluoride Effect on Root Demineralization</title><source>MEDLINE</source><source>SAGE Complete A-Z List</source><creator>Gao, X.-L. ; Pan, J.-S. ; Hsu, C.-Y.</creator><creatorcontrib>Gao, X.-L. ; Pan, J.-S. ; Hsu, C.-Y.</creatorcontrib><description>Although the individual cariostatic effects of laser and fluoride have been shown, the combined effect of CO2 laser and fluoride on root demineralization remains uncertain and was the main aim of this study. By using a pH-cycling system and Polarized Light Microscopy, we demonstrated the synergistic effect of fluoride combined with CO2 laser treatment on reducing root demineralization. The mean lesion depths (in μm) for each group were 160 ± 14 (Control), 113 ± 8 (Laser treatment alone), 111 ± 6 (Fluoride treatment alone), and 25 ± 7 (Fluoride followed by laser treatment). A significant laser-enhanced fluoride uptake, characterized by the ToF-SIMS analysis, was revealed by the 37% and 400% increments in loosely and firmly bound fluorides (both p < 0.002) in laser-irradiated areas, compared with the non-irradiated controls. In conclusion, there is a significant synergistic effect of combined CO2 laser and fluoride treatment on the inhibition of root demineralization, possibly due to laser-enhanced fluoride uptake in the root.</description><identifier>ISSN: 0022-0345</identifier><identifier>EISSN: 1544-0591</identifier><identifier>DOI: 10.1177/154405910608501009</identifier><identifier>PMID: 16998132</identifier><identifier>CODEN: JDREAF</identifier><language>eng</language><publisher>United States: SAGE Publications</publisher><subject>Carbon Dioxide ; Cariostatic Agents - administration & dosage ; Cariostatic Agents - pharmacokinetics ; Cariostatic Agents - pharmacology ; Combined Modality Therapy ; Dentistry ; Fluorides, Topical - administration & dosage ; Fluorides, Topical - pharmacokinetics ; Fluorides, Topical - pharmacology ; Humans ; Laser Therapy ; Microscopy, Polarization ; Root Caries - prevention & control ; Root Caries - therapy ; Tooth Demineralization - prevention & control ; Tooth Demineralization - therapy ; Tooth Root - drug effects ; Tooth Root - radiation effects</subject><ispartof>Journal of dental research, 2006-10, Vol.85 (10), p.919-923</ispartof><rights>International and American Associations for Dental Research</rights><rights>Copyright American Association for Dental Research/American Academy of Implant Dentistry Oct 2006</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c494t-cc24a0bcce4a2e4be89bb2422e6471b603dd71e4fe60a5459724c51b65fc33293</citedby><cites>FETCH-LOGICAL-c494t-cc24a0bcce4a2e4be89bb2422e6471b603dd71e4fe60a5459724c51b65fc33293</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/154405910608501009$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/154405910608501009$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,780,784,21818,27923,27924,43620,43621</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16998132$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gao, X.-L.</creatorcontrib><creatorcontrib>Pan, J.-S.</creatorcontrib><creatorcontrib>Hsu, C.-Y.</creatorcontrib><title>Laser-Fluoride Effect on Root Demineralization</title><title>Journal of dental research</title><addtitle>J Dent Res</addtitle><description>Although the individual cariostatic effects of laser and fluoride have been shown, the combined effect of CO2 laser and fluoride on root demineralization remains uncertain and was the main aim of this study. By using a pH-cycling system and Polarized Light Microscopy, we demonstrated the synergistic effect of fluoride combined with CO2 laser treatment on reducing root demineralization. The mean lesion depths (in μm) for each group were 160 ± 14 (Control), 113 ± 8 (Laser treatment alone), 111 ± 6 (Fluoride treatment alone), and 25 ± 7 (Fluoride followed by laser treatment). A significant laser-enhanced fluoride uptake, characterized by the ToF-SIMS analysis, was revealed by the 37% and 400% increments in loosely and firmly bound fluorides (both p < 0.002) in laser-irradiated areas, compared with the non-irradiated controls. In conclusion, there is a significant synergistic effect of combined CO2 laser and fluoride treatment on the inhibition of root demineralization, possibly due to laser-enhanced fluoride uptake in the root.</description><subject>Carbon Dioxide</subject><subject>Cariostatic Agents - administration & dosage</subject><subject>Cariostatic Agents - pharmacokinetics</subject><subject>Cariostatic Agents - pharmacology</subject><subject>Combined Modality Therapy</subject><subject>Dentistry</subject><subject>Fluorides, Topical - administration & dosage</subject><subject>Fluorides, Topical - pharmacokinetics</subject><subject>Fluorides, Topical - pharmacology</subject><subject>Humans</subject><subject>Laser Therapy</subject><subject>Microscopy, Polarization</subject><subject>Root Caries - prevention & control</subject><subject>Root Caries - therapy</subject><subject>Tooth Demineralization - prevention & control</subject><subject>Tooth Demineralization - therapy</subject><subject>Tooth Root - drug effects</subject><subject>Tooth Root - radiation effects</subject><issn>0022-0345</issn><issn>1544-0591</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNqFkEFLw0AQhRdRbK3-AQ9SPHhLO7s7m2SPUlsVCoLoOWw2E0lJsnU3OeivN6UFQUHnMjDzvTfMY-ySw4zzJJlzhQhKc4ghVcAB9BEb74bRbnrMxgBCRCBRjdhZCBsArkUqT9mIx1qnXIoxm61NIB-t6t75qqDpsizJdlPXTp-d66Z31FQteVNXn6arXHvOTkpTB7o49Al7XS1fFg_R-un-cXG7jixq7CJrBRrIrSU0gjCnVOe5QCEoxoTnMciiSDhhSTEYhUonAq0aFqq0UgotJ-xm77v17r2n0GVNFSzVtWnJ9SGL06FA8X9BrmWKnOMAXv8AN6737fBEJkCjEjGKARJ7yHoXgqcy2_qqMf4j45DtMs9-Zz6Irg7Ofd5Q8S05hDwA8z0QzBt9n_3D8guCZIay</recordid><startdate>20061001</startdate><enddate>20061001</enddate><creator>Gao, X.-L.</creator><creator>Pan, J.-S.</creator><creator>Hsu, C.-Y.</creator><general>SAGE Publications</general><general>SAGE PUBLICATIONS, INC</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RQ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>S0X</scope><scope>U9A</scope><scope>7QP</scope><scope>7X8</scope></search><sort><creationdate>20061001</creationdate><title>Laser-Fluoride Effect on Root Demineralization</title><author>Gao, X.-L. ; Pan, J.-S. ; Hsu, C.-Y.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c494t-cc24a0bcce4a2e4be89bb2422e6471b603dd71e4fe60a5459724c51b65fc33293</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Carbon Dioxide</topic><topic>Cariostatic Agents - administration & dosage</topic><topic>Cariostatic Agents - pharmacokinetics</topic><topic>Cariostatic Agents - pharmacology</topic><topic>Combined Modality Therapy</topic><topic>Dentistry</topic><topic>Fluorides, Topical - administration & dosage</topic><topic>Fluorides, Topical - pharmacokinetics</topic><topic>Fluorides, Topical - pharmacology</topic><topic>Humans</topic><topic>Laser Therapy</topic><topic>Microscopy, Polarization</topic><topic>Root Caries - prevention & control</topic><topic>Root Caries - therapy</topic><topic>Tooth Demineralization - prevention & control</topic><topic>Tooth Demineralization - therapy</topic><topic>Tooth Root - drug effects</topic><topic>Tooth Root - radiation effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gao, X.-L.</creatorcontrib><creatorcontrib>Pan, J.-S.</creatorcontrib><creatorcontrib>Hsu, C.-Y.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Career & Technical Education Database</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>SIRS Editorial</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of dental research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gao, X.-L.</au><au>Pan, J.-S.</au><au>Hsu, C.-Y.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Laser-Fluoride Effect on Root Demineralization</atitle><jtitle>Journal of dental research</jtitle><addtitle>J Dent Res</addtitle><date>2006-10-01</date><risdate>2006</risdate><volume>85</volume><issue>10</issue><spage>919</spage><epage>923</epage><pages>919-923</pages><issn>0022-0345</issn><eissn>1544-0591</eissn><coden>JDREAF</coden><abstract>Although the individual cariostatic effects of laser and fluoride have been shown, the combined effect of CO2 laser and fluoride on root demineralization remains uncertain and was the main aim of this study. By using a pH-cycling system and Polarized Light Microscopy, we demonstrated the synergistic effect of fluoride combined with CO2 laser treatment on reducing root demineralization. The mean lesion depths (in μm) for each group were 160 ± 14 (Control), 113 ± 8 (Laser treatment alone), 111 ± 6 (Fluoride treatment alone), and 25 ± 7 (Fluoride followed by laser treatment). A significant laser-enhanced fluoride uptake, characterized by the ToF-SIMS analysis, was revealed by the 37% and 400% increments in loosely and firmly bound fluorides (both p < 0.002) in laser-irradiated areas, compared with the non-irradiated controls. In conclusion, there is a significant synergistic effect of combined CO2 laser and fluoride treatment on the inhibition of root demineralization, possibly due to laser-enhanced fluoride uptake in the root.</abstract><cop>United States</cop><pub>SAGE Publications</pub><pmid>16998132</pmid><doi>10.1177/154405910608501009</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-0345 |
| ispartof | Journal of dental research, 2006-10, Vol.85 (10), p.919-923 |
| issn | 0022-0345 1544-0591 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_68888051 |
| source | MEDLINE; SAGE Complete A-Z List |
| subjects | Carbon Dioxide Cariostatic Agents - administration & dosage Cariostatic Agents - pharmacokinetics Cariostatic Agents - pharmacology Combined Modality Therapy Dentistry Fluorides, Topical - administration & dosage Fluorides, Topical - pharmacokinetics Fluorides, Topical - pharmacology Humans Laser Therapy Microscopy, Polarization Root Caries - prevention & control Root Caries - therapy Tooth Demineralization - prevention & control Tooth Demineralization - therapy Tooth Root - drug effects Tooth Root - radiation effects |
| title | Laser-Fluoride Effect on Root Demineralization |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-08T12%3A18%3A29IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Laser-Fluoride%20Effect%20on%20Root%20Demineralization&rft.jtitle=Journal%20of%20dental%20research&rft.au=Gao,%20X.-L.&rft.date=2006-10-01&rft.volume=85&rft.issue=10&rft.spage=919&rft.epage=923&rft.pages=919-923&rft.issn=0022-0345&rft.eissn=1544-0591&rft.coden=JDREAF&rft_id=info:doi/10.1177/154405910608501009&rft_dat=%3Cproquest_cross%3E19384114%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=209452642&rft_id=info:pmid/16998132&rft_sage_id=10.1177_154405910608501009&rfr_iscdi=true |