In situ dye injection bile leakage test of the graft in living donor liver transplantation
Bile leakage after living donor liver transplantation (LDLT) remains a serious problem, resulting in lower survival rates. The aim of this study is to clarify the benefits of in situ leakage testing of the cut surface of grafts in LDLT. A total of 135 LDLTs were analyzed. The patients were divided i...
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| Veröffentlicht in: | Transplantation 2005-11, Vol.80 (10), p.1398-1401 |
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| creator | SUEHIRO, Taketoshi SHIMADA, Mitsuo KISHIKAWA, Keiji SHIMURA, Tatsuo SOEJIMA, Yuji YOSHIZUMI, Tomoharu HASHIMOTO, Kohji MOCHIDA, Yasushi MAEHARA, Yoshihiko KUWANO, Hiroyuki |
| description | Bile leakage after living donor liver transplantation (LDLT) remains a serious problem, resulting in lower survival rates. The aim of this study is to clarify the benefits of in situ leakage testing of the cut surface of grafts in LDLT.
A total of 135 LDLTs were analyzed. The patients were divided into the following two groups according to the in situ dye injection leakage test of the cut surface: test group (n=40) and control group (n=40). The incidence of bile leakage and the risk factors were identified by analyzing the recipients, donors, and transplantation variables.
Bile leakage occurred in 12.5% (10/80) of LDLTs. In the control group, there were nine cases of bile leakage (22.5%). On the other hand, there was only one case (2.5%) of bile leakage in the test group (P |
| doi_str_mv | 10.1097/01.tp.0000181166.63783.69 |
| format | Article |
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A total of 135 LDLTs were analyzed. The patients were divided into the following two groups according to the in situ dye injection leakage test of the cut surface: test group (n=40) and control group (n=40). The incidence of bile leakage and the risk factors were identified by analyzing the recipients, donors, and transplantation variables.
Bile leakage occurred in 12.5% (10/80) of LDLTs. In the control group, there were nine cases of bile leakage (22.5%). On the other hand, there was only one case (2.5%) of bile leakage in the test group (P<0.05). The bile leakage case in the test group was resolved preservationally. However, 2 of the 9 (22.2%) bile leakage cases in the control group required surgery.
Although there is biliary complication, especially bile leakage from the cut surface, as an inevitable consequence of LDLT, this study suggests that there is advantage in conducting bile leakage testing to minimize the incidence of bile leakage from the cut surface, which is associated with a high risk of graft failure.</description><identifier>ISSN: 0041-1337</identifier><identifier>EISSN: 1534-6080</identifier><identifier>DOI: 10.1097/01.tp.0000181166.63783.69</identifier><identifier>PMID: 16340781</identifier><identifier>CODEN: TRPLAU</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott</publisher><subject>Adult ; Bile Ducts - surgery ; Biological and medical sciences ; Child ; Female ; Fundamental and applied biological sciences. Psychology ; Fundamental immunology ; Gallbladder Diseases - etiology ; Gallbladder Diseases - surgery ; Humans ; Indocyanine Green ; Liver Transplantation - adverse effects ; Liver Transplantation - methods ; Living Donors ; Male ; Medical sciences ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Tissue, organ and graft immunology</subject><ispartof>Transplantation, 2005-11, Vol.80 (10), p.1398-1401</ispartof><rights>2006 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c493t-87f7121018947c386a30be07b3ecea15de5bbf32d9bdf121b3c356a0ca3d3c533</citedby><cites>FETCH-LOGICAL-c493t-87f7121018947c386a30be07b3ecea15de5bbf32d9bdf121b3c356a0ca3d3c533</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782,27911,27912</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17352907$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16340781$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>SUEHIRO, Taketoshi</creatorcontrib><creatorcontrib>SHIMADA, Mitsuo</creatorcontrib><creatorcontrib>KISHIKAWA, Keiji</creatorcontrib><creatorcontrib>SHIMURA, Tatsuo</creatorcontrib><creatorcontrib>SOEJIMA, Yuji</creatorcontrib><creatorcontrib>YOSHIZUMI, Tomoharu</creatorcontrib><creatorcontrib>HASHIMOTO, Kohji</creatorcontrib><creatorcontrib>MOCHIDA, Yasushi</creatorcontrib><creatorcontrib>MAEHARA, Yoshihiko</creatorcontrib><creatorcontrib>KUWANO, Hiroyuki</creatorcontrib><title>In situ dye injection bile leakage test of the graft in living donor liver transplantation</title><title>Transplantation</title><addtitle>Transplantation</addtitle><description>Bile leakage after living donor liver transplantation (LDLT) remains a serious problem, resulting in lower survival rates. The aim of this study is to clarify the benefits of in situ leakage testing of the cut surface of grafts in LDLT.
A total of 135 LDLTs were analyzed. The patients were divided into the following two groups according to the in situ dye injection leakage test of the cut surface: test group (n=40) and control group (n=40). The incidence of bile leakage and the risk factors were identified by analyzing the recipients, donors, and transplantation variables.
Bile leakage occurred in 12.5% (10/80) of LDLTs. In the control group, there were nine cases of bile leakage (22.5%). On the other hand, there was only one case (2.5%) of bile leakage in the test group (P<0.05). The bile leakage case in the test group was resolved preservationally. However, 2 of the 9 (22.2%) bile leakage cases in the control group required surgery.
Although there is biliary complication, especially bile leakage from the cut surface, as an inevitable consequence of LDLT, this study suggests that there is advantage in conducting bile leakage testing to minimize the incidence of bile leakage from the cut surface, which is associated with a high risk of graft failure.</description><subject>Adult</subject><subject>Bile Ducts - surgery</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Female</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Fundamental immunology</subject><subject>Gallbladder Diseases - etiology</subject><subject>Gallbladder Diseases - surgery</subject><subject>Humans</subject><subject>Indocyanine Green</subject><subject>Liver Transplantation - adverse effects</subject><subject>Liver Transplantation - methods</subject><subject>Living Donors</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Tissue, organ and graft immunology</subject><issn>0041-1337</issn><issn>1534-6080</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkU1v1DAQhi1URJfCX0DuodwSPJnEH8eqaqFSJS5w4WI5zmRxm01S24vUf4-XrrRH5jIa6ZmZd-Zl7BJEDcKoLwLqvNaiBGgAKWuJSmMtzRu2gQ7bSgotzthGiBYqQFTn7H1Kj4XvUKl37BwktkJp2LBf9zNPIe_58EI8zI_kc1hm3oeJ-ETuyW2JZ0qZLyPPv4lvoxtzAfkU_oR5y4dlXuKhoMhzdHNaJzdndxjygb0d3ZTo4zFfsJ93tz9uvlUP37_e31w_VL41mCutRgUNlFNMqzxq6VD0JFSP5MlBN1DX9yM2g-mHsYA9euykE97hgL5DvGCfX-eucXneF612F5KnqQihZZ-s1FqrrtH_BUG1Egw2BTSvoI9LSpFGu8awc_HFgrAHB6wAm1d7csD-c8BKU3o_HZfs-x0Np87jywtwdQRc8m4ay9N8SCdOYdcYofAv3wSPuQ</recordid><startdate>20051127</startdate><enddate>20051127</enddate><creator>SUEHIRO, Taketoshi</creator><creator>SHIMADA, Mitsuo</creator><creator>KISHIKAWA, Keiji</creator><creator>SHIMURA, Tatsuo</creator><creator>SOEJIMA, Yuji</creator><creator>YOSHIZUMI, Tomoharu</creator><creator>HASHIMOTO, Kohji</creator><creator>MOCHIDA, Yasushi</creator><creator>MAEHARA, Yoshihiko</creator><creator>KUWANO, Hiroyuki</creator><general>Lippincott</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>20051127</creationdate><title>In situ dye injection bile leakage test of the graft in living donor liver transplantation</title><author>SUEHIRO, Taketoshi ; SHIMADA, Mitsuo ; KISHIKAWA, Keiji ; SHIMURA, Tatsuo ; SOEJIMA, Yuji ; YOSHIZUMI, Tomoharu ; HASHIMOTO, Kohji ; MOCHIDA, Yasushi ; MAEHARA, Yoshihiko ; KUWANO, Hiroyuki</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c493t-87f7121018947c386a30be07b3ecea15de5bbf32d9bdf121b3c356a0ca3d3c533</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Adult</topic><topic>Bile Ducts - surgery</topic><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Female</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Fundamental immunology</topic><topic>Gallbladder Diseases - etiology</topic><topic>Gallbladder Diseases - surgery</topic><topic>Humans</topic><topic>Indocyanine Green</topic><topic>Liver Transplantation - adverse effects</topic><topic>Liver Transplantation - methods</topic><topic>Living Donors</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Tissue, organ and graft immunology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>SUEHIRO, Taketoshi</creatorcontrib><creatorcontrib>SHIMADA, Mitsuo</creatorcontrib><creatorcontrib>KISHIKAWA, Keiji</creatorcontrib><creatorcontrib>SHIMURA, Tatsuo</creatorcontrib><creatorcontrib>SOEJIMA, Yuji</creatorcontrib><creatorcontrib>YOSHIZUMI, Tomoharu</creatorcontrib><creatorcontrib>HASHIMOTO, Kohji</creatorcontrib><creatorcontrib>MOCHIDA, Yasushi</creatorcontrib><creatorcontrib>MAEHARA, Yoshihiko</creatorcontrib><creatorcontrib>KUWANO, Hiroyuki</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Transplantation</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>SUEHIRO, Taketoshi</au><au>SHIMADA, Mitsuo</au><au>KISHIKAWA, Keiji</au><au>SHIMURA, Tatsuo</au><au>SOEJIMA, Yuji</au><au>YOSHIZUMI, Tomoharu</au><au>HASHIMOTO, Kohji</au><au>MOCHIDA, Yasushi</au><au>MAEHARA, Yoshihiko</au><au>KUWANO, Hiroyuki</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>In situ dye injection bile leakage test of the graft in living donor liver transplantation</atitle><jtitle>Transplantation</jtitle><addtitle>Transplantation</addtitle><date>2005-11-27</date><risdate>2005</risdate><volume>80</volume><issue>10</issue><spage>1398</spage><epage>1401</epage><pages>1398-1401</pages><issn>0041-1337</issn><eissn>1534-6080</eissn><coden>TRPLAU</coden><abstract>Bile leakage after living donor liver transplantation (LDLT) remains a serious problem, resulting in lower survival rates. The aim of this study is to clarify the benefits of in situ leakage testing of the cut surface of grafts in LDLT.
A total of 135 LDLTs were analyzed. The patients were divided into the following two groups according to the in situ dye injection leakage test of the cut surface: test group (n=40) and control group (n=40). The incidence of bile leakage and the risk factors were identified by analyzing the recipients, donors, and transplantation variables.
Bile leakage occurred in 12.5% (10/80) of LDLTs. In the control group, there were nine cases of bile leakage (22.5%). On the other hand, there was only one case (2.5%) of bile leakage in the test group (P<0.05). The bile leakage case in the test group was resolved preservationally. However, 2 of the 9 (22.2%) bile leakage cases in the control group required surgery.
Although there is biliary complication, especially bile leakage from the cut surface, as an inevitable consequence of LDLT, this study suggests that there is advantage in conducting bile leakage testing to minimize the incidence of bile leakage from the cut surface, which is associated with a high risk of graft failure.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott</pub><pmid>16340781</pmid><doi>10.1097/01.tp.0000181166.63783.69</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Adult Bile Ducts - surgery Biological and medical sciences Child Female Fundamental and applied biological sciences. Psychology Fundamental immunology Gallbladder Diseases - etiology Gallbladder Diseases - surgery Humans Indocyanine Green Liver Transplantation - adverse effects Liver Transplantation - methods Living Donors Male Medical sciences Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Tissue, organ and graft immunology |
| title | In situ dye injection bile leakage test of the graft in living donor liver transplantation |
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