A One-Pot Preparation of 1,3-Disubstituted Azetidines

A straightforward synthesis of 1,3-disubstituted azetidines has been accomplished via the alkylation of a primary amine with the bis-triflate of a 2-substituted-1,3-propanediol species. This transformation is carried out in one reaction vessel, and elimination of the alkylating reagent is generally...

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Veröffentlicht in:	Journal of organic chemistry 2006-09, Vol.71 (20), p.7885-7887
Hauptverfasser:	Hillier, Michael C, Chen, Cheng-yi
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkylation Amines - chemistry Azetidines - chemical synthesis Chemistry Exact sciences and technology Heterocyclic compounds Heterocyclic compounds with only one n hetero atom and condensed derivatives Methods Organic chemistry Preparations and properties Propylene Glycols - chemistry
Online-Zugang:	Volltext
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