The Scaffolding Protein CG-NAP/AKAP450 Is a Critical Integrating Component of the LFA-1-Induced Signaling Complex in Migratory T Cells

T cell migration represents a complex highly coordinated process involving participation of surface receptor/ligand interactions, cytoskeletal rearrangements, and phosphorylation-dependent signaling cascades. Members of the A-kinase anchoring protein (AKAP) family of giant scaffolding proteins can a...

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Veröffentlicht in:	Journal of Immunology 2005-12, Vol.175 (12), p.7811-7818
Hauptverfasser:	El Homasany, Basma Salah El Din, Volkov, Yuri, Takahashi, Mikiko, Ono, Yoshitaka, Keryer, Guy, Delouvee, Annie, Looby, Eileen, Long, Aideen, Kelleher, Dermot
Format:	Artikel
Sprache:	eng
Schlagworte:	A Kinase Anchor Proteins Adaptor Proteins, Signal Transducing - metabolism Adaptor Proteins, Signal Transducing - physiology Cell Line, Tumor Cells, Cultured Centrosome - metabolism Chemotaxis, Leukocyte Cytoskeletal Proteins - metabolism Cytoskeletal Proteins - physiology Golgi Apparatus - metabolism Humans Lymphocyte Function-Associated Antigen-1 - metabolism Lymphocyte Function-Associated Antigen-1 - physiology Microtubules - metabolism Multiprotein Complexes - physiology Signal Transduction T-Lymphocytes - cytology T-Lymphocytes - physiology
Online-Zugang:	Volltext
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