Effects of the renal natriuretic peptide urodilatin (ularitide) in patients with decompensated chronic heart failure: A double-blind, placebo-controlled, ascending-dose trial

Urodilatin (ularitide), a natriuretic peptide, is produced within the kidneys. The aim of this study was to define the role of 24-hour intravenous infusions of urodilatin in the treatment of decompensated chronic heart failure (DHF). In this randomized, double-blind, ascending-dose safety study, 24...

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Veröffentlicht in:	The American heart journal 2005-12, Vol.150 (6), p.1239.e1-1239.e8
Hauptverfasser:	Mitrovic, Veselin, Lüss, Hartmut, Nitsche, Klaus, Forssmann, Kristin, Maronde, Erik, Fricke, Katrin, Forssmann, Wolf-Georg, Meyer, Markus
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aqueous solutions Atrial Natriuretic Factor - pharmacology Blood pressure Chronic Disease Dose-Response Relationship, Drug Double-Blind Method Drug dosages Drug therapy Female Heart failure Heart Failure - metabolism Heart Function Tests Heart rate Humans Intubation ISDN Kidney - metabolism Male Middle Aged Patient Selection Peptide Fragments - pharmacology Peptides Placebos Respiratory Function Tests Rodents
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