BAP1 and breast cancer risk
BAP1 whose protein interacts with BRCA1 was analysed in a series of 47 French familial breast cancer cases negatively tested for BRCA1/2 mutations. The lack of detection of deleterious mutations suggests that BAP1 is not a high risk breast cancer predisposing gene. However, a common identified varia...
Gespeichert in:
| Veröffentlicht in: | Familial cancer 2005-01, Vol.4 (4), p.273-277 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 277 |
|---|---|
| container_issue | 4 |
| container_start_page | 273 |
| container_title | Familial cancer |
| container_volume | 4 |
| creator | Coupier, Isabelle Cousin, Pierre-Yves Hughes, David Legoix-Né, Patricia Trehin, Alexandra Sinilnikova, Olga M Stoppa-Lyonnet, Dominique |
| description | BAP1 whose protein interacts with BRCA1 was analysed in a series of 47 French familial breast cancer cases negatively tested for BRCA1/2 mutations. The lack of detection of deleterious mutations suggests that BAP1 is not a high risk breast cancer predisposing gene. However, a common identified variant, rs123602, may be tested in sporadic cases as candidate for moderate risk. |
| doi_str_mv | 10.1007/s10689-005-2833-4 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_68882954</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>68882954</sourcerecordid><originalsourceid>FETCH-LOGICAL-c326t-656528761cfdd2cad8fe9be7394ace59d6c72f3e0adde93cb28476ede7d1130e3</originalsourceid><addsrcrecordid>eNpdkE1LAzEQhoMotlZ_gAiyePAWnUx283GsxS8o6EHPIZvMQmu7W5PuwX_vlhYETzMwz_syPIxdCrgTAPo-C1DGcoCKo5GSl0dsLCotuUaLx8Muh6tVACN2lvMSAAGlPmUjoWQpDOCYXT1M30Xh21jUiXzeFsG3gVKRFvnrnJ00fpXp4jAn7PPp8WP2wudvz6-z6ZwHiWrLVaUqNFqJ0MSIwUfTkK1JS1v6QJWNKmhsJIGPkawMNZpSK4qkoxASSE7Y7b53k7rvnvLWrRc50GrlW-r67JQxBm1VDuDNP3DZ9akdfnMoKgQhLA6Q2EMhdTknatwmLdY-_TgBbqfN7bW5QZvbaXO74utDcV-vKf4lDp7kL0A_ZXQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>215201192</pqid></control><display><type>article</type><title>BAP1 and breast cancer risk</title><source>MEDLINE</source><source>SpringerLink Journals</source><creator>Coupier, Isabelle ; Cousin, Pierre-Yves ; Hughes, David ; Legoix-Né, Patricia ; Trehin, Alexandra ; Sinilnikova, Olga M ; Stoppa-Lyonnet, Dominique</creator><creatorcontrib>Coupier, Isabelle ; Cousin, Pierre-Yves ; Hughes, David ; Legoix-Né, Patricia ; Trehin, Alexandra ; Sinilnikova, Olga M ; Stoppa-Lyonnet, Dominique</creatorcontrib><description>BAP1 whose protein interacts with BRCA1 was analysed in a series of 47 French familial breast cancer cases negatively tested for BRCA1/2 mutations. The lack of detection of deleterious mutations suggests that BAP1 is not a high risk breast cancer predisposing gene. However, a common identified variant, rs123602, may be tested in sporadic cases as candidate for moderate risk.</description><identifier>ISSN: 1389-9600</identifier><identifier>EISSN: 1573-7292</identifier><identifier>DOI: 10.1007/s10689-005-2833-4</identifier><identifier>PMID: 16341802</identifier><identifier>CODEN: FCAAAJ</identifier><language>eng</language><publisher>Netherlands: Springer Nature B.V</publisher><subject>Adult ; Breast cancer ; Breast Neoplasms - genetics ; DNA Mutational Analysis ; Female ; Genetic Predisposition to Disease ; Humans ; Middle Aged ; Polymerase Chain Reaction ; Polymorphism, Single Nucleotide ; Risk Factors ; Tumor Suppressor Proteins - genetics ; Ubiquitin Thiolesterase - genetics</subject><ispartof>Familial cancer, 2005-01, Vol.4 (4), p.273-277</ispartof><rights>Springer 2005</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c326t-656528761cfdd2cad8fe9be7394ace59d6c72f3e0adde93cb28476ede7d1130e3</citedby><cites>FETCH-LOGICAL-c326t-656528761cfdd2cad8fe9be7394ace59d6c72f3e0adde93cb28476ede7d1130e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16341802$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Coupier, Isabelle</creatorcontrib><creatorcontrib>Cousin, Pierre-Yves</creatorcontrib><creatorcontrib>Hughes, David</creatorcontrib><creatorcontrib>Legoix-Né, Patricia</creatorcontrib><creatorcontrib>Trehin, Alexandra</creatorcontrib><creatorcontrib>Sinilnikova, Olga M</creatorcontrib><creatorcontrib>Stoppa-Lyonnet, Dominique</creatorcontrib><title>BAP1 and breast cancer risk</title><title>Familial cancer</title><addtitle>Fam Cancer</addtitle><description>BAP1 whose protein interacts with BRCA1 was analysed in a series of 47 French familial breast cancer cases negatively tested for BRCA1/2 mutations. The lack of detection of deleterious mutations suggests that BAP1 is not a high risk breast cancer predisposing gene. However, a common identified variant, rs123602, may be tested in sporadic cases as candidate for moderate risk.</description><subject>Adult</subject><subject>Breast cancer</subject><subject>Breast Neoplasms - genetics</subject><subject>DNA Mutational Analysis</subject><subject>Female</subject><subject>Genetic Predisposition to Disease</subject><subject>Humans</subject><subject>Middle Aged</subject><subject>Polymerase Chain Reaction</subject><subject>Polymorphism, Single Nucleotide</subject><subject>Risk Factors</subject><subject>Tumor Suppressor Proteins - genetics</subject><subject>Ubiquitin Thiolesterase - genetics</subject><issn>1389-9600</issn><issn>1573-7292</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNpdkE1LAzEQhoMotlZ_gAiyePAWnUx283GsxS8o6EHPIZvMQmu7W5PuwX_vlhYETzMwz_syPIxdCrgTAPo-C1DGcoCKo5GSl0dsLCotuUaLx8Muh6tVACN2lvMSAAGlPmUjoWQpDOCYXT1M30Xh21jUiXzeFsG3gVKRFvnrnJ00fpXp4jAn7PPp8WP2wudvz6-z6ZwHiWrLVaUqNFqJ0MSIwUfTkK1JS1v6QJWNKmhsJIGPkawMNZpSK4qkoxASSE7Y7b53k7rvnvLWrRc50GrlW-r67JQxBm1VDuDNP3DZ9akdfnMoKgQhLA6Q2EMhdTknatwmLdY-_TgBbqfN7bW5QZvbaXO74utDcV-vKf4lDp7kL0A_ZXQ</recordid><startdate>20050101</startdate><enddate>20050101</enddate><creator>Coupier, Isabelle</creator><creator>Cousin, Pierre-Yves</creator><creator>Hughes, David</creator><creator>Legoix-Né, Patricia</creator><creator>Trehin, Alexandra</creator><creator>Sinilnikova, Olga M</creator><creator>Stoppa-Lyonnet, Dominique</creator><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K9-</scope><scope>K9.</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>20050101</creationdate><title>BAP1 and breast cancer risk</title><author>Coupier, Isabelle ; Cousin, Pierre-Yves ; Hughes, David ; Legoix-Né, Patricia ; Trehin, Alexandra ; Sinilnikova, Olga M ; Stoppa-Lyonnet, Dominique</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c326t-656528761cfdd2cad8fe9be7394ace59d6c72f3e0adde93cb28476ede7d1130e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Adult</topic><topic>Breast cancer</topic><topic>Breast Neoplasms - genetics</topic><topic>DNA Mutational Analysis</topic><topic>Female</topic><topic>Genetic Predisposition to Disease</topic><topic>Humans</topic><topic>Middle Aged</topic><topic>Polymerase Chain Reaction</topic><topic>Polymorphism, Single Nucleotide</topic><topic>Risk Factors</topic><topic>Tumor Suppressor Proteins - genetics</topic><topic>Ubiquitin Thiolesterase - genetics</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Coupier, Isabelle</creatorcontrib><creatorcontrib>Cousin, Pierre-Yves</creatorcontrib><creatorcontrib>Hughes, David</creatorcontrib><creatorcontrib>Legoix-Né, Patricia</creatorcontrib><creatorcontrib>Trehin, Alexandra</creatorcontrib><creatorcontrib>Sinilnikova, Olga M</creatorcontrib><creatorcontrib>Stoppa-Lyonnet, Dominique</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Familial cancer</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Coupier, Isabelle</au><au>Cousin, Pierre-Yves</au><au>Hughes, David</au><au>Legoix-Né, Patricia</au><au>Trehin, Alexandra</au><au>Sinilnikova, Olga M</au><au>Stoppa-Lyonnet, Dominique</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>BAP1 and breast cancer risk</atitle><jtitle>Familial cancer</jtitle><addtitle>Fam Cancer</addtitle><date>2005-01-01</date><risdate>2005</risdate><volume>4</volume><issue>4</issue><spage>273</spage><epage>277</epage><pages>273-277</pages><issn>1389-9600</issn><eissn>1573-7292</eissn><coden>FCAAAJ</coden><abstract>BAP1 whose protein interacts with BRCA1 was analysed in a series of 47 French familial breast cancer cases negatively tested for BRCA1/2 mutations. The lack of detection of deleterious mutations suggests that BAP1 is not a high risk breast cancer predisposing gene. However, a common identified variant, rs123602, may be tested in sporadic cases as candidate for moderate risk.</abstract><cop>Netherlands</cop><pub>Springer Nature B.V</pub><pmid>16341802</pmid><doi>10.1007/s10689-005-2833-4</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1389-9600 |
| ispartof | Familial cancer, 2005-01, Vol.4 (4), p.273-277 |
| issn | 1389-9600 1573-7292 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_68882954 |
| source | MEDLINE; SpringerLink Journals |
| subjects | Adult Breast cancer Breast Neoplasms - genetics DNA Mutational Analysis Female Genetic Predisposition to Disease Humans Middle Aged Polymerase Chain Reaction Polymorphism, Single Nucleotide Risk Factors Tumor Suppressor Proteins - genetics Ubiquitin Thiolesterase - genetics |
| title | BAP1 and breast cancer risk |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-01T13%3A27%3A06IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=BAP1%20and%20breast%20cancer%20risk&rft.jtitle=Familial%20cancer&rft.au=Coupier,%20Isabelle&rft.date=2005-01-01&rft.volume=4&rft.issue=4&rft.spage=273&rft.epage=277&rft.pages=273-277&rft.issn=1389-9600&rft.eissn=1573-7292&rft.coden=FCAAAJ&rft_id=info:doi/10.1007/s10689-005-2833-4&rft_dat=%3Cproquest_cross%3E68882954%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=215201192&rft_id=info:pmid/16341802&rfr_iscdi=true |