Enterochromaffin cell hyperplasia and decreased serotonin transporter in a mouse model of postinfectious bowel dysfunction

Patients with postinfective irritable bowel syndrome and Trichinella spiralis‐infected mice share many features including visceral hypersensitivity and disordered motility. We assessed enterochromaffin (EC) numbers and serotonin transporter (SERT) using National Institute of Health (NIH) female mice...

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Veröffentlicht in:	Neurogastroenterology and motility 2005-12, Vol.17 (6), p.863-870
Hauptverfasser:	Wheatcroft, J., Wakelin, D., Smith, A., Mahoney, C. R., Mawe, G., Spiller, R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents - therapeutic use Cell Count Digestive System - pathology Digestive System - physiopathology Enterochromaffin Cells - pathology Hydrocortisone - therapeutic use Hyperplasia - pathology immune Immunohistochemistry Intestinal Mucosa - pathology intestine Jejunum - metabolism Jejunum - pathology Mast Cells - metabolism Mast Cells - pathology Mice Mice, Inbred C57BL Mice, Knockout post‐infectious serotonin Serotonin Plasma Membrane Transport Proteins - genetics Serotonin Plasma Membrane Transport Proteins - physiology T-Lymphocytes - metabolism T-Lymphocytes - pathology Trichinella Trichinellosis - pathology
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