B23 is a downstream target of polyamine-modulated CK2

Our previous studies have shown that the overexpression of ornithine decarboxylase (ODC), the rate-limiting enzyme in polyamine biosynthesis, increases the enzymatic activity of the polyamine-responsive enzyme casein kinase 2 (CK2). Because CK2 is known to preferentially associate with the nuclear m...

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Veröffentlicht in:	Molecular and cellular biochemistry 2005-06, Vol.274 (1-2), p.103-114
Hauptverfasser:	Lawson, Kathryn, Larentowicz, Laura, Laury-Kleintop, Lisa, Gilmour, Susan K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apigenin - pharmacology Biosynthesis Casein Kinase II - antagonists & inhibitors Casein Kinase II - metabolism Cell Nucleolus - metabolism Cells, Cultured Dichlororibofuranosylbenzimidazole - pharmacology Eflornithine - pharmacology Enzymatic activity Enzymes Keratinocytes - drug effects Keratinocytes - metabolism Kinases Mice Mice, Transgenic Nuclear Matrix - metabolism Nuclear Proteins - metabolism Ornithine Decarboxylase - biosynthesis Ornithine Decarboxylase - genetics Ornithine Decarboxylase Inhibitors Phosphorylation Polyamines Polyamines - metabolism Signal Transduction
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