The Effect of Insulin-Like Growth Factor I on Healing of Colonic Anastomoses in Cortisone-Treated Rats

This study was designed to investigate whether intraperitoneally injected insulin-like growth factor I is able to protect colonic healing from the adverse effects of hydrocortisone therapy. Eighty female Wistar rats were randomized into four groups (20 rats each). After resection of a segment of tra...

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Veröffentlicht in:	Diseases of the colon & rectum 2006-09, Vol.49 (9), p.1431-1438
Hauptverfasser:	Mantzoros, I, Kanellos, I, Angelopoulos, S, Koliakos, G, Pramateftakis, M G, Kanellos, D, Zacharakis, E, Zaraboukas, T, Betsis, D
Format:	Artikel
Sprache:	eng
Schlagworte:	Anastomosis, Surgical Animals Anti-Inflammatory Agents - pharmacology Biological and medical sciences Bones, joints and connective tissue. Antiinflammatory agents Colon - metabolism Colon - physiology Colon - surgery Female Gastroenterology. Liver. Pancreas. Abdomen Hydrocortisone - pharmacology Hydroxyproline - metabolism Injections, Intraperitoneal Insulin-Like Growth Factor I - pharmacology Medical sciences Pharmacology. Drug treatments Rats Rats, Wistar Tensile Strength Wound Healing - drug effects
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