Adult Medulloblastoma Relapse Visualized by In-111 Octreotide Scintigraphy
A 31-year-old woman with a history of desmoplastic medulloblastoma in the right cerebellar hemisphere had undergone a resection. Magnetic resonance imaging (MRI) was indicated with the aim of ruling out a relapse, but the results were inconclusive. In-111-DTPA octreotide scintigraphy was performed....
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Veröffentlicht in: | Clinical nuclear medicine 2006-10, Vol.31 (10), p.633-635 |
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creator | Infante, Jose R Rayo, Juan I Serrano, Justo Domínguez, María L García, Lucia Sánchez, Roman |
description | A 31-year-old woman with a history of desmoplastic medulloblastoma in the right cerebellar hemisphere had undergone a resection. Magnetic resonance imaging (MRI) was indicated with the aim of ruling out a relapse, but the results were inconclusive. In-111-DTPA octreotide scintigraphy was performed. Planar images and SPECT scan obtained after radiolabeled octreotide injection revealed elevated uptake in the posterior fossa suggestive of relapse. The patient underwent a craniotomy for surgical resection. Although medulloblastoma is the most common pediatric central nervous system malignancy, it is rare in adults with few cases studied with somatostatin receptor scintigraphy and described in the existing literature. |
doi_str_mv | 10.1097/01.rlu.0000237972.48108.8d |
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Magnetic resonance imaging (MRI) was indicated with the aim of ruling out a relapse, but the results were inconclusive. In-111-DTPA octreotide scintigraphy was performed. Planar images and SPECT scan obtained after radiolabeled octreotide injection revealed elevated uptake in the posterior fossa suggestive of relapse. The patient underwent a craniotomy for surgical resection. Although medulloblastoma is the most common pediatric central nervous system malignancy, it is rare in adults with few cases studied with somatostatin receptor scintigraphy and described in the existing literature.</description><identifier>ISSN: 0363-9762</identifier><identifier>EISSN: 1536-0229</identifier><identifier>DOI: 10.1097/01.rlu.0000237972.48108.8d</identifier><identifier>PMID: 16985373</identifier><language>eng</language><publisher>United States: Lippincott Williams & Wilkins, Inc</publisher><subject>Adult ; Cerebellar Neoplasms - diagnostic imaging ; Female ; Humans ; Medulloblastoma - diagnostic imaging ; Neoplasm Recurrence, Local - diagnostic imaging ; Octreotide - analogs & derivatives ; Pentetic Acid - analogs & derivatives ; Radionuclide Imaging ; Radiopharmaceuticals</subject><ispartof>Clinical nuclear medicine, 2006-10, Vol.31 (10), p.633-635</ispartof><rights>2006 Lippincott Williams & Wilkins, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c3053-bc2ecf68035ff9e4157ad68b5ec36b178edd4dc3a6f81a111928ce9d1a713c2f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,27928,27929</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16985373$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Infante, Jose R</creatorcontrib><creatorcontrib>Rayo, Juan I</creatorcontrib><creatorcontrib>Serrano, Justo</creatorcontrib><creatorcontrib>Domínguez, María L</creatorcontrib><creatorcontrib>García, Lucia</creatorcontrib><creatorcontrib>Sánchez, Roman</creatorcontrib><title>Adult Medulloblastoma Relapse Visualized by In-111 Octreotide Scintigraphy</title><title>Clinical nuclear medicine</title><addtitle>Clin Nucl Med</addtitle><description>A 31-year-old woman with a history of desmoplastic medulloblastoma in the right cerebellar hemisphere had undergone a resection. Magnetic resonance imaging (MRI) was indicated with the aim of ruling out a relapse, but the results were inconclusive. In-111-DTPA octreotide scintigraphy was performed. Planar images and SPECT scan obtained after radiolabeled octreotide injection revealed elevated uptake in the posterior fossa suggestive of relapse. The patient underwent a craniotomy for surgical resection. Although medulloblastoma is the most common pediatric central nervous system malignancy, it is rare in adults with few cases studied with somatostatin receptor scintigraphy and described in the existing literature.</description><subject>Adult</subject><subject>Cerebellar Neoplasms - diagnostic imaging</subject><subject>Female</subject><subject>Humans</subject><subject>Medulloblastoma - diagnostic imaging</subject><subject>Neoplasm Recurrence, Local - diagnostic imaging</subject><subject>Octreotide - analogs & derivatives</subject><subject>Pentetic Acid - analogs & derivatives</subject><subject>Radionuclide Imaging</subject><subject>Radiopharmaceuticals</subject><issn>0363-9762</issn><issn>1536-0229</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkFlLxDAQx4Mouh5fQYoPvrVmkjaHbyKeKILXa0iTqVvNbtekRdZPb3UXHBiGgf8BP0KOgBZAtTyhUMQwFHQcxqWWrCgVUFUov0EmUHGRU8b0JplQLniupWA7ZDeld0pBgCi3yQ4IrSou-YTcnvkh9Nk9jid0dbCp72Y2e8RgFwmz1zYNNrTf6LN6md3McwDIHlwfsetbj9mTa-d9-xbtYrrcJ1uNDQkP1nePvFxePJ9f53cPVzfnZ3e547Tiee0YukYoyqum0VhCJa0Xqq7QcVGDVOh96R23olFgxz7NlEPtwUrgjjV8jxyvchex-xww9WbWJoch2Dl2QzJCKVFpLUfh6UroYpdSxMYsYjuzcWmAml-ShoIZSZp_kuaPpFF-NB-uW4Z6hv7fukY3CsqV4KsLPcb0EYYvjGaKNvTTv0hOJcsZpQJ-v3xc4PwHHMGAaA</recordid><startdate>200610</startdate><enddate>200610</enddate><creator>Infante, Jose R</creator><creator>Rayo, Juan I</creator><creator>Serrano, Justo</creator><creator>Domínguez, María L</creator><creator>García, Lucia</creator><creator>Sánchez, Roman</creator><general>Lippincott Williams & Wilkins, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200610</creationdate><title>Adult Medulloblastoma Relapse Visualized by In-111 Octreotide Scintigraphy</title><author>Infante, Jose R ; Rayo, Juan I ; Serrano, Justo ; Domínguez, María L ; García, Lucia ; Sánchez, Roman</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3053-bc2ecf68035ff9e4157ad68b5ec36b178edd4dc3a6f81a111928ce9d1a713c2f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Adult</topic><topic>Cerebellar Neoplasms - diagnostic imaging</topic><topic>Female</topic><topic>Humans</topic><topic>Medulloblastoma - diagnostic imaging</topic><topic>Neoplasm Recurrence, Local - diagnostic imaging</topic><topic>Octreotide - analogs & derivatives</topic><topic>Pentetic Acid - analogs & derivatives</topic><topic>Radionuclide Imaging</topic><topic>Radiopharmaceuticals</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Infante, Jose R</creatorcontrib><creatorcontrib>Rayo, Juan I</creatorcontrib><creatorcontrib>Serrano, Justo</creatorcontrib><creatorcontrib>Domínguez, María L</creatorcontrib><creatorcontrib>García, Lucia</creatorcontrib><creatorcontrib>Sánchez, Roman</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Clinical nuclear medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Infante, Jose R</au><au>Rayo, Juan I</au><au>Serrano, Justo</au><au>Domínguez, María L</au><au>García, Lucia</au><au>Sánchez, Roman</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Adult Medulloblastoma Relapse Visualized by In-111 Octreotide Scintigraphy</atitle><jtitle>Clinical nuclear medicine</jtitle><addtitle>Clin Nucl Med</addtitle><date>2006-10</date><risdate>2006</risdate><volume>31</volume><issue>10</issue><spage>633</spage><epage>635</epage><pages>633-635</pages><issn>0363-9762</issn><eissn>1536-0229</eissn><abstract>A 31-year-old woman with a history of desmoplastic medulloblastoma in the right cerebellar hemisphere had undergone a resection. Magnetic resonance imaging (MRI) was indicated with the aim of ruling out a relapse, but the results were inconclusive. In-111-DTPA octreotide scintigraphy was performed. Planar images and SPECT scan obtained after radiolabeled octreotide injection revealed elevated uptake in the posterior fossa suggestive of relapse. The patient underwent a craniotomy for surgical resection. Although medulloblastoma is the most common pediatric central nervous system malignancy, it is rare in adults with few cases studied with somatostatin receptor scintigraphy and described in the existing literature.</abstract><cop>United States</cop><pub>Lippincott Williams & Wilkins, Inc</pub><pmid>16985373</pmid><doi>10.1097/01.rlu.0000237972.48108.8d</doi><tpages>3</tpages></addata></record> |
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subjects | Adult Cerebellar Neoplasms - diagnostic imaging Female Humans Medulloblastoma - diagnostic imaging Neoplasm Recurrence, Local - diagnostic imaging Octreotide - analogs & derivatives Pentetic Acid - analogs & derivatives Radionuclide Imaging Radiopharmaceuticals |
title | Adult Medulloblastoma Relapse Visualized by In-111 Octreotide Scintigraphy |
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