Seroprevalence of rubella antibodies among antenatal patients in the Western Cape
To determine the seroprevalence of rubella virus infection among antenatal patients aged between 15 and 45 years in the Western Cape province of South Africa, in order to provide data to determine the need for vaccination to protect women of childbearing age. A cross-sectional study. Setting. Virolo...
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| Veröffentlicht in: | South African medical journal 2005-09, Vol.95 (9), p.688-690 |
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| creator | CORCORAN, Craig HARDIE, Diana R |
| description | To determine the seroprevalence of rubella virus infection among antenatal patients aged between 15 and 45 years in the Western Cape province of South Africa, in order to provide data to determine the need for vaccination to protect women of childbearing age.
A cross-sectional study. Setting. Virology laboratory, Groote Schuur Hospital, National Health Laboratory Service (NHLS), South Africa.
One thousand two hundred provincial serum specimens from participants in the 2003 Department of Health antenatal HIV/syphilis serosurvey were selected from the 4 districts of the Western Cape. The specimens were age-stratified and screened qualitatively for rubella immunoglobulin G (IgG) antibodies by means of a commercial immunoassay during October 2004.
Within the Western Cape a total of 95.3% of women in the 15-24-year age group, 97.5% in the 25-34-year group and 98% in the 35-45-year age group were immune to rubella. There was no statistically significant difference in the rate of rubella susceptibility between the 4 districts tested.
The study is an important step in addressing the seroprevalence of rubella infection in women of childbearing age in South Africa. Further information is needed on rubella seroprevalence from the other provinces in South Africa as well as formal implementation of rubella and congenital rubella syndrome surveillance to determine the feasibility of routine rubella immunisation. |
| format | Article |
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A cross-sectional study. Setting. Virology laboratory, Groote Schuur Hospital, National Health Laboratory Service (NHLS), South Africa.
One thousand two hundred provincial serum specimens from participants in the 2003 Department of Health antenatal HIV/syphilis serosurvey were selected from the 4 districts of the Western Cape. The specimens were age-stratified and screened qualitatively for rubella immunoglobulin G (IgG) antibodies by means of a commercial immunoassay during October 2004.
Within the Western Cape a total of 95.3% of women in the 15-24-year age group, 97.5% in the 25-34-year group and 98% in the 35-45-year age group were immune to rubella. There was no statistically significant difference in the rate of rubella susceptibility between the 4 districts tested.
The study is an important step in addressing the seroprevalence of rubella infection in women of childbearing age in South Africa. Further information is needed on rubella seroprevalence from the other provinces in South Africa as well as formal implementation of rubella and congenital rubella syndrome surveillance to determine the feasibility of routine rubella immunisation.</description><identifier>ISSN: 0256-9574</identifier><identifier>PMID: 16327929</identifier><identifier>CODEN: SAMJAF</identifier><language>eng</language><publisher>Pinelands: Medical Association of South Africa</publisher><subject>Adolescent ; Adult ; Biological and medical sciences ; Cross-Sectional Studies ; Disease Susceptibility - epidemiology ; Disease Susceptibility - immunology ; Female ; Human viral diseases ; Humans ; Immunoglobulin G - blood ; Infectious diseases ; Medical sciences ; Middle Aged ; Pregnancy ; Pregnancy Complications, Infectious - epidemiology ; Pregnancy Complications, Infectious - immunology ; Pregnancy Complications, Infectious - prevention & control ; Rubella - epidemiology ; Rubella - immunology ; Rubella - prevention & control ; Seroepidemiologic Studies ; South Africa - epidemiology ; Viral diseases ; Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye</subject><ispartof>South African medical journal, 2005-09, Vol.95 (9), p.688-690</ispartof><rights>2005 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17147566$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16327929$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>CORCORAN, Craig</creatorcontrib><creatorcontrib>HARDIE, Diana R</creatorcontrib><title>Seroprevalence of rubella antibodies among antenatal patients in the Western Cape</title><title>South African medical journal</title><addtitle>S Afr Med J</addtitle><description>To determine the seroprevalence of rubella virus infection among antenatal patients aged between 15 and 45 years in the Western Cape province of South Africa, in order to provide data to determine the need for vaccination to protect women of childbearing age.
A cross-sectional study. Setting. Virology laboratory, Groote Schuur Hospital, National Health Laboratory Service (NHLS), South Africa.
One thousand two hundred provincial serum specimens from participants in the 2003 Department of Health antenatal HIV/syphilis serosurvey were selected from the 4 districts of the Western Cape. The specimens were age-stratified and screened qualitatively for rubella immunoglobulin G (IgG) antibodies by means of a commercial immunoassay during October 2004.
Within the Western Cape a total of 95.3% of women in the 15-24-year age group, 97.5% in the 25-34-year group and 98% in the 35-45-year age group were immune to rubella. There was no statistically significant difference in the rate of rubella susceptibility between the 4 districts tested.
The study is an important step in addressing the seroprevalence of rubella infection in women of childbearing age in South Africa. Further information is needed on rubella seroprevalence from the other provinces in South Africa as well as formal implementation of rubella and congenital rubella syndrome surveillance to determine the feasibility of routine rubella immunisation.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Cross-Sectional Studies</subject><subject>Disease Susceptibility - epidemiology</subject><subject>Disease Susceptibility - immunology</subject><subject>Female</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Immunoglobulin G - blood</subject><subject>Infectious diseases</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Pregnancy</subject><subject>Pregnancy Complications, Infectious - epidemiology</subject><subject>Pregnancy Complications, Infectious - immunology</subject><subject>Pregnancy Complications, Infectious - prevention & control</subject><subject>Rubella - epidemiology</subject><subject>Rubella - immunology</subject><subject>Rubella - prevention & control</subject><subject>Seroepidemiologic Studies</subject><subject>South Africa - epidemiology</subject><subject>Viral diseases</subject><subject>Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye</subject><issn>0256-9574</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpF0E1LxDAQBuAeFHf9-AuSi94KbZNOk6MsfsGCiIrHMk0mGmnTmqSC_94urngaZnh4eZmDbF1UNeSqbsQqO47xo1j2WsFRtiqBV42q1Dp7fKIwToG-sCeviY2WhbmjvkeGPrluNI4iw2H0b7sDeUzYswmTI58ic56ld2KvFBMFzzY40Wl2aLGPdLafJ9nLzfXz5i7fPtzeb662-VRxlXJtDYfS6IKDFRwIuK1QSLDG1NoglVYWnTaqMkYooaWsG9OUlUSutWoWfpJd_uZOYfyclwLt4KLeNfc0zrEFKUEA1As838O5G8i0U3ADhu_27wkLuNgDjBp7G9BrF_9dU4qmBuA_51ZlzQ</recordid><startdate>20050901</startdate><enddate>20050901</enddate><creator>CORCORAN, Craig</creator><creator>HARDIE, Diana R</creator><general>Medical Association of South Africa</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>20050901</creationdate><title>Seroprevalence of rubella antibodies among antenatal patients in the Western Cape</title><author>CORCORAN, Craig ; HARDIE, Diana R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p239t-cfd361dc036f436e63f2a486fdd5cdae1f80bcd92dd494c8857d7128a3cc97e63</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Cross-Sectional Studies</topic><topic>Disease Susceptibility - epidemiology</topic><topic>Disease Susceptibility - immunology</topic><topic>Female</topic><topic>Human viral diseases</topic><topic>Humans</topic><topic>Immunoglobulin G - blood</topic><topic>Infectious diseases</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Pregnancy</topic><topic>Pregnancy Complications, Infectious - epidemiology</topic><topic>Pregnancy Complications, Infectious - immunology</topic><topic>Pregnancy Complications, Infectious - prevention & control</topic><topic>Rubella - epidemiology</topic><topic>Rubella - immunology</topic><topic>Rubella - prevention & control</topic><topic>Seroepidemiologic Studies</topic><topic>South Africa - epidemiology</topic><topic>Viral diseases</topic><topic>Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>CORCORAN, Craig</creatorcontrib><creatorcontrib>HARDIE, Diana R</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>South African medical journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>CORCORAN, Craig</au><au>HARDIE, Diana R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Seroprevalence of rubella antibodies among antenatal patients in the Western Cape</atitle><jtitle>South African medical journal</jtitle><addtitle>S Afr Med J</addtitle><date>2005-09-01</date><risdate>2005</risdate><volume>95</volume><issue>9</issue><spage>688</spage><epage>690</epage><pages>688-690</pages><issn>0256-9574</issn><coden>SAMJAF</coden><abstract>To determine the seroprevalence of rubella virus infection among antenatal patients aged between 15 and 45 years in the Western Cape province of South Africa, in order to provide data to determine the need for vaccination to protect women of childbearing age.
A cross-sectional study. Setting. Virology laboratory, Groote Schuur Hospital, National Health Laboratory Service (NHLS), South Africa.
One thousand two hundred provincial serum specimens from participants in the 2003 Department of Health antenatal HIV/syphilis serosurvey were selected from the 4 districts of the Western Cape. The specimens were age-stratified and screened qualitatively for rubella immunoglobulin G (IgG) antibodies by means of a commercial immunoassay during October 2004.
Within the Western Cape a total of 95.3% of women in the 15-24-year age group, 97.5% in the 25-34-year group and 98% in the 35-45-year age group were immune to rubella. There was no statistically significant difference in the rate of rubella susceptibility between the 4 districts tested.
The study is an important step in addressing the seroprevalence of rubella infection in women of childbearing age in South Africa. Further information is needed on rubella seroprevalence from the other provinces in South Africa as well as formal implementation of rubella and congenital rubella syndrome surveillance to determine the feasibility of routine rubella immunisation.</abstract><cop>Pinelands</cop><pub>Medical Association of South Africa</pub><pmid>16327929</pmid><tpages>3</tpages></addata></record> |
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| source | MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; African Journals Online (Open Access); Sabinet African Journals Open Access Collection; Alma/SFX Local Collection |
| subjects | Adolescent Adult Biological and medical sciences Cross-Sectional Studies Disease Susceptibility - epidemiology Disease Susceptibility - immunology Female Human viral diseases Humans Immunoglobulin G - blood Infectious diseases Medical sciences Middle Aged Pregnancy Pregnancy Complications, Infectious - epidemiology Pregnancy Complications, Infectious - immunology Pregnancy Complications, Infectious - prevention & control Rubella - epidemiology Rubella - immunology Rubella - prevention & control Seroepidemiologic Studies South Africa - epidemiology Viral diseases Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye |
| title | Seroprevalence of rubella antibodies among antenatal patients in the Western Cape |
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