Canine mdr1 gene mutation in Japan

Frequency of the 4-bp deletion mutant in canine mdr1 gene was examined in 193 dogs of eight breeds in Japan. The mutant allele was found in Collies, Australian Shepherds, and Shetland Sheepdogs, where its respective frequencies were 58.3%, 33.3%, and 1.2%. The MDR1 protein was detected on peripheral...

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Veröffentlicht in:	Journal of Veterinary Medical Science 2005, Vol.67(11), pp.1103-1107
Hauptverfasser:	Kawabata, A.(Tokyo Univ. of Agriculture and Technology, Fuchu (Japan). Faculty of Agriculture), Momoi, Y, Inoue Murayama, M, Iwasaki, T
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals canine CHIEN DNA Primers DOGS Dogs - genetics GENE Gene Frequency GENES Genes, MDR - genetics GLICOPROTEINAS GLYCOPROTEINE GLYCOPROTEINS IVERMECTIN IVERMECTINA IVERMECTINE JAPAN JAPON Leukocytes, Mononuclear - metabolism MDR1 MUTACION MUTATION Mutation, Missense - genetics PERRO Rhodamine 123 - metabolism Verapamil
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