Effects of chronic ethanol administration on brain protein levels: A proteomic investigation using 2-D DIGE system

The effects of chronic ethanol treatment on the brain proteome were investigated in the long-fin striped strain of zebrafish Danio rerio. Prolonged exposure to 0.5% (v/v) ethanol resulted in the development of tolerance to the ethanol-induced disruption of normal swimming behavior. This behavioral t...

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Veröffentlicht in:	European journal of pharmacology 2006-10, Vol.547 (1), p.75-82
Hauptverfasser:	Damodaran, Senthilkumar, Dlugos, Cynthia A., Wood, Troy D., Rabin, Richard A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcoholism and acute alcohol poisoning Animals Behavior, Animal - drug effects Biological and medical sciences Brain - drug effects Brain - metabolism Central Nervous System Depressants - pharmacology Danio rerio DIGE Electrophoresis, Gel, Two-Dimensional - methods Ethanol Ethanol - pharmacology Freshwater Medical sciences Pharmacology. Drug treatments Proteomics Proteomics - methods Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization Swimming - physiology Time Factors Toxicology Zebrafish Zebrafish Proteins - analysis
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