Serum kynurenic acid positively correlates with cardiovascular disease risk factor, homocysteine: a study in stroke patients

KYNA, an antagonist of ionotropic glutamate receptors and alpha7 nicotinic receptors, has been found as well in the brain as in the periphery. The altered metabolism of KYNA, especially its deficiency, can lead to the enhanced glutamate-mediated excitotoxicity, and was suggested to be a factor contr...

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