Bullous pemphigoid triggered by influenza vaccination? Ecological study in Galicia, Spain
Summary Background Influenza vaccination has been suggested to be a trigger for bullous pemphigoid (BP). In our area most new patients with BP are admitted to hospital. Objectives To detect a difference in the rate of admissions to hospital for BP during population influenza vaccination programmes...
Gespeichert in:
| Veröffentlicht in: | British journal of dermatology (1951) 2006-10, Vol.155 (4), p.820-823 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 823 |
|---|---|
| container_issue | 4 |
| container_start_page | 820 |
| container_title | British journal of dermatology (1951) |
| container_volume | 155 |
| creator | García‐Doval, I. Mayo, E. Nogueira Fariña, J. Cruces, M.J. |
| description | Summary
Background Influenza vaccination has been suggested to be a trigger for bullous pemphigoid (BP). In our area most new patients with BP are admitted to hospital.
Objectives To detect a difference in the rate of admissions to hospital for BP during population influenza vaccination programmes, which are mainly targeted at individuals aged 65 years or older, start in the last week of September and last for 2 months.
Methods An ecological study in Galicia, north‐west Spain (1997–2005), restricted to people aged 65 years or older. Using Poisson regression, results were controlled for mean age of admission and percentage of the population vaccinated each year.
Results There were 29 admissions registered during ‘vaccination periods’ (i.e. approximately 10 weeks per year, including the period of vaccination and two further weeks), and 158 during nonvaccination periods (the rest of the year). The incidence rate ratio of admissions for BP in vaccination vs. nonvaccination periods was 0·85 (95% confidence interval 0·57–1·27, P = 0·43).
Conclusions Our data do not support the hypothesis of influenza vaccination being an important trigger for severe BP on a population level. |
| doi_str_mv | 10.1111/j.1365-2133.2006.07411.x |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_68848966</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>68848966</sourcerecordid><originalsourceid>FETCH-LOGICAL-p1931-b6d941fe206a68dfe589b8422c70a28f6475c6268f33362852a5d8ac1172cdb3</originalsourceid><addsrcrecordid>eNpFkMtOwzAQRS0EoqXwC8grViT4kTjOAiFaSgFVYkE3rCzHdoIr50Ee0PL1JLTAbO5I92ikOQBAjHzcz9Xax5SFHsGU-gQh5qMowNjfHIDxX3EIxgihyEMxoyNw0jRrhDBFIToGI8xiFgY0GIPXaedc2TWwMnn1ZrPSatjWNstMbTRMttAWqetM8SXhh1TKFrK1ZXED56p0ZWaVdLBpOz1wcCGdVVZewpdK2uIUHKXSNeZsnxOwup-vZg_e8nnxOLtdehWOKfYSpuMAp4YgJhnXqQl5nPCAEBUhSXjKgihUjDCeUkoZ4SGRoeZSYRwRpRM6ARe7s1VdvnemaUVuG2Wck4Xp_xKM84DHjPXg-R7sktxoUdU2l_VW_Lrogesd8Gmd2f73SAzOxVoMasWgVgzOxY9zsRHTp7tho98MGHSF</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>68848966</pqid></control><display><type>article</type><title>Bullous pemphigoid triggered by influenza vaccination? Ecological study in Galicia, Spain</title><source>Oxford University Press Journals All Titles (1996-Current)</source><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>García‐Doval, I. ; Mayo, E. ; Nogueira Fariña, J. ; Cruces, M.J.</creator><creatorcontrib>García‐Doval, I. ; Mayo, E. ; Nogueira Fariña, J. ; Cruces, M.J.</creatorcontrib><description>Summary
Background Influenza vaccination has been suggested to be a trigger for bullous pemphigoid (BP). In our area most new patients with BP are admitted to hospital.
Objectives To detect a difference in the rate of admissions to hospital for BP during population influenza vaccination programmes, which are mainly targeted at individuals aged 65 years or older, start in the last week of September and last for 2 months.
Methods An ecological study in Galicia, north‐west Spain (1997–2005), restricted to people aged 65 years or older. Using Poisson regression, results were controlled for mean age of admission and percentage of the population vaccinated each year.
Results There were 29 admissions registered during ‘vaccination periods’ (i.e. approximately 10 weeks per year, including the period of vaccination and two further weeks), and 158 during nonvaccination periods (the rest of the year). The incidence rate ratio of admissions for BP in vaccination vs. nonvaccination periods was 0·85 (95% confidence interval 0·57–1·27, P = 0·43).
Conclusions Our data do not support the hypothesis of influenza vaccination being an important trigger for severe BP on a population level.</description><identifier>ISSN: 0007-0963</identifier><identifier>EISSN: 1365-2133</identifier><identifier>DOI: 10.1111/j.1365-2133.2006.07411.x</identifier><identifier>PMID: 16965434</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>adverse effects ; Aged ; Aged, 80 and over ; bullous pemphigoid ; Hospitalization - statistics & numerical data ; Humans ; Incidence ; influenza vaccines ; Influenza Vaccines - adverse effects ; Pemphigoid, Bullous - epidemiology ; Pemphigoid, Bullous - etiology ; Spain - epidemiology ; Vaccination - adverse effects</subject><ispartof>British journal of dermatology (1951), 2006-10, Vol.155 (4), p.820-823</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1365-2133.2006.07411.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1365-2133.2006.07411.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16965434$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>García‐Doval, I.</creatorcontrib><creatorcontrib>Mayo, E.</creatorcontrib><creatorcontrib>Nogueira Fariña, J.</creatorcontrib><creatorcontrib>Cruces, M.J.</creatorcontrib><title>Bullous pemphigoid triggered by influenza vaccination? Ecological study in Galicia, Spain</title><title>British journal of dermatology (1951)</title><addtitle>Br J Dermatol</addtitle><description>Summary
Background Influenza vaccination has been suggested to be a trigger for bullous pemphigoid (BP). In our area most new patients with BP are admitted to hospital.
Objectives To detect a difference in the rate of admissions to hospital for BP during population influenza vaccination programmes, which are mainly targeted at individuals aged 65 years or older, start in the last week of September and last for 2 months.
Methods An ecological study in Galicia, north‐west Spain (1997–2005), restricted to people aged 65 years or older. Using Poisson regression, results were controlled for mean age of admission and percentage of the population vaccinated each year.
Results There were 29 admissions registered during ‘vaccination periods’ (i.e. approximately 10 weeks per year, including the period of vaccination and two further weeks), and 158 during nonvaccination periods (the rest of the year). The incidence rate ratio of admissions for BP in vaccination vs. nonvaccination periods was 0·85 (95% confidence interval 0·57–1·27, P = 0·43).
Conclusions Our data do not support the hypothesis of influenza vaccination being an important trigger for severe BP on a population level.</description><subject>adverse effects</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>bullous pemphigoid</subject><subject>Hospitalization - statistics & numerical data</subject><subject>Humans</subject><subject>Incidence</subject><subject>influenza vaccines</subject><subject>Influenza Vaccines - adverse effects</subject><subject>Pemphigoid, Bullous - epidemiology</subject><subject>Pemphigoid, Bullous - etiology</subject><subject>Spain - epidemiology</subject><subject>Vaccination - adverse effects</subject><issn>0007-0963</issn><issn>1365-2133</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkMtOwzAQRS0EoqXwC8grViT4kTjOAiFaSgFVYkE3rCzHdoIr50Ee0PL1JLTAbO5I92ikOQBAjHzcz9Xax5SFHsGU-gQh5qMowNjfHIDxX3EIxgihyEMxoyNw0jRrhDBFIToGI8xiFgY0GIPXaedc2TWwMnn1ZrPSatjWNstMbTRMttAWqetM8SXhh1TKFrK1ZXED56p0ZWaVdLBpOz1wcCGdVVZewpdK2uIUHKXSNeZsnxOwup-vZg_e8nnxOLtdehWOKfYSpuMAp4YgJhnXqQl5nPCAEBUhSXjKgihUjDCeUkoZ4SGRoeZSYRwRpRM6ARe7s1VdvnemaUVuG2Wck4Xp_xKM84DHjPXg-R7sktxoUdU2l_VW_Lrogesd8Gmd2f73SAzOxVoMasWgVgzOxY9zsRHTp7tho98MGHSF</recordid><startdate>200610</startdate><enddate>200610</enddate><creator>García‐Doval, I.</creator><creator>Mayo, E.</creator><creator>Nogueira Fariña, J.</creator><creator>Cruces, M.J.</creator><general>Blackwell Publishing Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>200610</creationdate><title>Bullous pemphigoid triggered by influenza vaccination? Ecological study in Galicia, Spain</title><author>García‐Doval, I. ; Mayo, E. ; Nogueira Fariña, J. ; Cruces, M.J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p1931-b6d941fe206a68dfe589b8422c70a28f6475c6268f33362852a5d8ac1172cdb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>adverse effects</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>bullous pemphigoid</topic><topic>Hospitalization - statistics & numerical data</topic><topic>Humans</topic><topic>Incidence</topic><topic>influenza vaccines</topic><topic>Influenza Vaccines - adverse effects</topic><topic>Pemphigoid, Bullous - epidemiology</topic><topic>Pemphigoid, Bullous - etiology</topic><topic>Spain - epidemiology</topic><topic>Vaccination - adverse effects</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>García‐Doval, I.</creatorcontrib><creatorcontrib>Mayo, E.</creatorcontrib><creatorcontrib>Nogueira Fariña, J.</creatorcontrib><creatorcontrib>Cruces, M.J.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>British journal of dermatology (1951)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>García‐Doval, I.</au><au>Mayo, E.</au><au>Nogueira Fariña, J.</au><au>Cruces, M.J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Bullous pemphigoid triggered by influenza vaccination? Ecological study in Galicia, Spain</atitle><jtitle>British journal of dermatology (1951)</jtitle><addtitle>Br J Dermatol</addtitle><date>2006-10</date><risdate>2006</risdate><volume>155</volume><issue>4</issue><spage>820</spage><epage>823</epage><pages>820-823</pages><issn>0007-0963</issn><eissn>1365-2133</eissn><abstract>Summary
Background Influenza vaccination has been suggested to be a trigger for bullous pemphigoid (BP). In our area most new patients with BP are admitted to hospital.
Objectives To detect a difference in the rate of admissions to hospital for BP during population influenza vaccination programmes, which are mainly targeted at individuals aged 65 years or older, start in the last week of September and last for 2 months.
Methods An ecological study in Galicia, north‐west Spain (1997–2005), restricted to people aged 65 years or older. Using Poisson regression, results were controlled for mean age of admission and percentage of the population vaccinated each year.
Results There were 29 admissions registered during ‘vaccination periods’ (i.e. approximately 10 weeks per year, including the period of vaccination and two further weeks), and 158 during nonvaccination periods (the rest of the year). The incidence rate ratio of admissions for BP in vaccination vs. nonvaccination periods was 0·85 (95% confidence interval 0·57–1·27, P = 0·43).
Conclusions Our data do not support the hypothesis of influenza vaccination being an important trigger for severe BP on a population level.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>16965434</pmid><doi>10.1111/j.1365-2133.2006.07411.x</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0007-0963 |
| ispartof | British journal of dermatology (1951), 2006-10, Vol.155 (4), p.820-823 |
| issn | 0007-0963 1365-2133 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_68848966 |
| source | Oxford University Press Journals All Titles (1996-Current); MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | adverse effects Aged Aged, 80 and over bullous pemphigoid Hospitalization - statistics & numerical data Humans Incidence influenza vaccines Influenza Vaccines - adverse effects Pemphigoid, Bullous - epidemiology Pemphigoid, Bullous - etiology Spain - epidemiology Vaccination - adverse effects |
| title | Bullous pemphigoid triggered by influenza vaccination? Ecological study in Galicia, Spain |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-30T07%3A18%3A45IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Bullous%20pemphigoid%20triggered%20by%20influenza%20vaccination?%20Ecological%20study%20in%20Galicia,%20Spain&rft.jtitle=British%20journal%20of%20dermatology%20(1951)&rft.au=Garc%C3%ADa%E2%80%90Doval,%20I.&rft.date=2006-10&rft.volume=155&rft.issue=4&rft.spage=820&rft.epage=823&rft.pages=820-823&rft.issn=0007-0963&rft.eissn=1365-2133&rft_id=info:doi/10.1111/j.1365-2133.2006.07411.x&rft_dat=%3Cproquest_pubme%3E68848966%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=68848966&rft_id=info:pmid/16965434&rfr_iscdi=true |