Feasibility of an easily applicable method of ZAP-70 measurement in chronic lymphocytic leukemia in the routine flow cytometry setting: A methodological approach

Zeta-associated protein 70 (ZAP-70), determined by flow cytometry, has been advocated a surrogate marker of immunoglobulin (Ig)V(H) unmutated status in B chronic lymphocytic leukemia (CLL). The aim of the current study was to test the applicability of an easy flow cytometry protocol for ZAP-70 measu...

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Veröffentlicht in:	Annals of hematology 2006-11, Vol.85 (11), p.795-805
Hauptverfasser:	Passam, Freda, Tachynopoulou, Varvara, Skoumi, Dimitra, Tsompanakou, Aliki, Stavropoulos-Giokas, Aikaterini, Vadikolia, Chrysanthi, Anagnostopoulos, Achilles, Paterakis, Georgios
Format:	Artikel
Sprache:	eng
Schlagworte:	ADP-ribosyl Cyclase 1 - analysis Adult Aged Antigens, CD19 Biomarkers - analysis Case-Control Studies CD3 Complex Disease Progression Feasibility Studies Female Flow cytometry Flow Cytometry - methods Flow Cytometry - standards Humans Leukemia Leukemia, Lymphocytic, Chronic, B-Cell - diagnosis Leukemia, Lymphocytic, Chronic, B-Cell - enzymology Leukemia, Lymphocytic, Chronic, B-Cell - mortality Lymphocytes Male Methods Middle Aged Prognosis Reference Standards ROC Curve Survival Analysis ZAP-70 Protein-Tyrosine Kinase - analysis
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