Evaluation of the analgesic and anti-inflammatory effects of a Brazilian green propolis

Abstract Phamacological activities of a standard ethanol extract G1 from Brazilian green propolis, typified as BRP1, was evaluated in mouse models of pain and inflammation. Intraperitoneal injection (I. P.) of G1 inhibited acetic acid-induced abdominal constrictions with an ID 50 = 0.75 ± 0.05 mg/kg...

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Veröffentlicht in:	Planta medica 2006-08, Vol.72 (10), p.899-906
Hauptverfasser:	Paulino, N, Teixeira, C, Scremin, A, Dirsch, V.M, Vollmar, A.M, Abreu, S.R.L, Castro, S.L. de, Marcucci, M.C
Format:	Artikel
Sprache:	eng
Schlagworte:	analgesic effect Analgesics - isolation & purification Analgesics - therapeutic use animal disease models Animals anti-inflammatory activity Anti-Inflammatory Agents - isolation & purification Anti-Inflammatory Agents - therapeutic use Apoidea Biological and medical sciences Brazil Cell Line Chromatography, High Pressure Liquid cultured cells Drug Evaluation, Preclinical edema enzyme inhibition flavonoids Gene Expression Regulation - drug effects General pharmacology Humans Inflammation - drug therapy Male Medical sciences Mice neutrophils nitric oxide nitric oxide synthase Nitric Oxide Synthase Type II - genetics Nitric Oxide Synthase Type II - metabolism nitrites Original Paper Pain - drug therapy Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Plant Extracts - administration & dosage Plant Extracts - isolation & purification Plant Extracts - therapeutic use propolis Propolis - administration & dosage Propolis - chemistry Propolis - therapeutic use signal transduction tumor necrosis factor-alpha
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