Increased arterial wave reflections predict severe cardiovascular events in patients undergoing percutaneous coronary interventions
Aims Increased arterial wave reflections are associated with the presence and extent of coronary atherosclerosis and with cardiovascular mortality in selected populations. We prospectively evaluated their prognostic value in the short- and long-term following percutaneous coronary interventions (PCI...
Gespeichert in:
| Veröffentlicht in: | European heart journal 2005-12, Vol.26 (24), p.2657-2663 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 2663 |
|---|---|
| container_issue | 24 |
| container_start_page | 2657 |
| container_title | European heart journal |
| container_volume | 26 |
| creator | Weber, Thomas Auer, Johann O'Rourke, Michael F. Kvas, Erich Lassnig, Elisabeth Lamm, Gudrun Stark, Nina Rammer, Martin Eber, Bernd |
| description | Aims Increased arterial wave reflections are associated with the presence and extent of coronary atherosclerosis and with cardiovascular mortality in selected populations. We prospectively evaluated their prognostic value in the short- and long-term following percutaneous coronary interventions (PCIs). Methods and results We non-invasively quantified wave reflections [expressed as augmentation index corrected for heart rate of 75 b.p.m. (AIx@75)] using applanation tonometry of the radial artery and a validated transfer function to obtain the corresponding aortic values in 262 patients undergoing PCI. During 2-year follow-up, 61 patients reached the primary endpoint [death, myocardial infarction (MI), and restenosis]. Increasing tertiles of Alx@75 were related to the rate of patients reaching the primary endpoint [15.2, 20 and 35.3%, respectively (P=0.001)], as well as the secondary endpoints total mortality, myocardial infarction and death plus myocardial infarction (RR for the third vs. the first tertile 4.33, 3.25 and 3.46, respectively, P |
| doi_str_mv | 10.1093/eurheartj/ehi504 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_68838718</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>943983401</sourcerecordid><originalsourceid>FETCH-LOGICAL-c500t-c5b2176689915638d5230a443e396e9725d9a85f62b9c61d697dfb5e6ca952793</originalsourceid><addsrcrecordid>eNpdkUtv1DAUhS1ERYeBPStkIcEu1I_4tUTl0aJKLACpmo3lcW5aDxkn2Mm0rPnj9TSjVurGtuzvHt97DkJvKPlIieEnMKVrcGncnMB1EKR-hhZUMFYZWYvnaEGoEZWU-vIYvcx5QwjRksoX6JhKqrnUeoH-n0efwGVocNGBFFyHb9wOcIK2Az-GPmY8JGiCH3GGHSTA3qUm9DuX_dS5hMtlHDMOEQ9uDPfnKTaQrvoQr_AAyU-ji9BPGfs-9dGlfwUuf-3r9vqv0FHrugyvD_sS_f765dfpWXXx49v56aeLygtCxrKuGVVlHGOokFw3gnHi6poDNxKMYqIxTotWsrXxkjbSqKZdC5DeGcGU4Uv0YdYdUv93gjzabcgeum7uzhZDuFbFmSV69wTc9FOKpTfLqKi10pwUiMyQT33OxS47pLAtw1lK7D4d-5COndMpJW8PutN6C81jwSGOArw_AMVc17XJRR_yI6c4U4zwwlUzF_IItw_vLv2xUnEl7Nnlyq70T_N59V1Zxe8AQPSt8g</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>215487830</pqid></control><display><type>article</type><title>Increased arterial wave reflections predict severe cardiovascular events in patients undergoing percutaneous coronary interventions</title><source>Oxford University Press Journals All Titles (1996-Current)</source><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><creator>Weber, Thomas ; Auer, Johann ; O'Rourke, Michael F. ; Kvas, Erich ; Lassnig, Elisabeth ; Lamm, Gudrun ; Stark, Nina ; Rammer, Martin ; Eber, Bernd</creator><creatorcontrib>Weber, Thomas ; Auer, Johann ; O'Rourke, Michael F. ; Kvas, Erich ; Lassnig, Elisabeth ; Lamm, Gudrun ; Stark, Nina ; Rammer, Martin ; Eber, Bernd</creatorcontrib><description>Aims Increased arterial wave reflections are associated with the presence and extent of coronary atherosclerosis and with cardiovascular mortality in selected populations. We prospectively evaluated their prognostic value in the short- and long-term following percutaneous coronary interventions (PCIs). Methods and results We non-invasively quantified wave reflections [expressed as augmentation index corrected for heart rate of 75 b.p.m. (AIx@75)] using applanation tonometry of the radial artery and a validated transfer function to obtain the corresponding aortic values in 262 patients undergoing PCI. During 2-year follow-up, 61 patients reached the primary endpoint [death, myocardial infarction (MI), and restenosis]. Increasing tertiles of Alx@75 were related to the rate of patients reaching the primary endpoint [15.2, 20 and 35.3%, respectively (P=0.001)], as well as the secondary endpoints total mortality, myocardial infarction and death plus myocardial infarction (RR for the third vs. the first tertile 4.33, 3.25 and 3.46, respectively, P<0.05). In a multivariable Cox-regression model, AIx@75 added prognostic value above and beyond clinical risk factors, angiographic variables, and medications (RR 1.8, 95%CI 1.18–2.76 per increasing AIx@75-tertile, P<0.01). Conclusion Increased arterial wave reflections are independently associated with an increased risk for severe short- and long-term cardiovascular events in patients undergoing PCI.</description><identifier>ISSN: 0195-668X</identifier><identifier>EISSN: 1522-9645</identifier><identifier>DOI: 10.1093/eurheartj/ehi504</identifier><identifier>PMID: 16183688</identifier><language>eng</language><publisher>Oxford: Oxford University Press</publisher><subject>Aged ; Angina Pectoris - diagnosis ; Angina Pectoris - etiology ; Angioplasty ; Angioplasty, Balloon, Coronary ; Arteries ; Arteriosclerosis ; Atherosclerosis (general aspects, experimental research) ; Biological and medical sciences ; Blood and lymphatic vessels ; Blood Pressure - physiology ; Cardiology. Vascular system ; Coronary Angiography ; Coronary Artery Disease - diagnosis ; Coronary Artery Disease - physiopathology ; Coronary Artery Disease - therapy ; Coronary disease ; Coronary heart disease ; Coronary Stenosis - etiology ; Female ; Heart ; Hemodynamics - physiology ; Humans ; Male ; Medical sciences ; Middle Aged ; Myocardial Infarction - etiology ; Predictive Value of Tests ; Prognosis ; Prospective Studies ; Risk Factors ; Wave reflections</subject><ispartof>European heart journal, 2005-12, Vol.26 (24), p.2657-2663</ispartof><rights>2006 INIST-CNRS</rights><rights>Copyright Oxford University Press(England) Dec 2005</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c500t-c5b2176689915638d5230a443e396e9725d9a85f62b9c61d697dfb5e6ca952793</citedby><cites>FETCH-LOGICAL-c500t-c5b2176689915638d5230a443e396e9725d9a85f62b9c61d697dfb5e6ca952793</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17327203$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16183688$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Weber, Thomas</creatorcontrib><creatorcontrib>Auer, Johann</creatorcontrib><creatorcontrib>O'Rourke, Michael F.</creatorcontrib><creatorcontrib>Kvas, Erich</creatorcontrib><creatorcontrib>Lassnig, Elisabeth</creatorcontrib><creatorcontrib>Lamm, Gudrun</creatorcontrib><creatorcontrib>Stark, Nina</creatorcontrib><creatorcontrib>Rammer, Martin</creatorcontrib><creatorcontrib>Eber, Bernd</creatorcontrib><title>Increased arterial wave reflections predict severe cardiovascular events in patients undergoing percutaneous coronary interventions</title><title>European heart journal</title><addtitle>Eur Heart J</addtitle><description>Aims Increased arterial wave reflections are associated with the presence and extent of coronary atherosclerosis and with cardiovascular mortality in selected populations. We prospectively evaluated their prognostic value in the short- and long-term following percutaneous coronary interventions (PCIs). Methods and results We non-invasively quantified wave reflections [expressed as augmentation index corrected for heart rate of 75 b.p.m. (AIx@75)] using applanation tonometry of the radial artery and a validated transfer function to obtain the corresponding aortic values in 262 patients undergoing PCI. During 2-year follow-up, 61 patients reached the primary endpoint [death, myocardial infarction (MI), and restenosis]. Increasing tertiles of Alx@75 were related to the rate of patients reaching the primary endpoint [15.2, 20 and 35.3%, respectively (P=0.001)], as well as the secondary endpoints total mortality, myocardial infarction and death plus myocardial infarction (RR for the third vs. the first tertile 4.33, 3.25 and 3.46, respectively, P<0.05). In a multivariable Cox-regression model, AIx@75 added prognostic value above and beyond clinical risk factors, angiographic variables, and medications (RR 1.8, 95%CI 1.18–2.76 per increasing AIx@75-tertile, P<0.01). Conclusion Increased arterial wave reflections are independently associated with an increased risk for severe short- and long-term cardiovascular events in patients undergoing PCI.</description><subject>Aged</subject><subject>Angina Pectoris - diagnosis</subject><subject>Angina Pectoris - etiology</subject><subject>Angioplasty</subject><subject>Angioplasty, Balloon, Coronary</subject><subject>Arteries</subject><subject>Arteriosclerosis</subject><subject>Atherosclerosis (general aspects, experimental research)</subject><subject>Biological and medical sciences</subject><subject>Blood and lymphatic vessels</subject><subject>Blood Pressure - physiology</subject><subject>Cardiology. Vascular system</subject><subject>Coronary Angiography</subject><subject>Coronary Artery Disease - diagnosis</subject><subject>Coronary Artery Disease - physiopathology</subject><subject>Coronary Artery Disease - therapy</subject><subject>Coronary disease</subject><subject>Coronary heart disease</subject><subject>Coronary Stenosis - etiology</subject><subject>Female</subject><subject>Heart</subject><subject>Hemodynamics - physiology</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Myocardial Infarction - etiology</subject><subject>Predictive Value of Tests</subject><subject>Prognosis</subject><subject>Prospective Studies</subject><subject>Risk Factors</subject><subject>Wave reflections</subject><issn>0195-668X</issn><issn>1522-9645</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkUtv1DAUhS1ERYeBPStkIcEu1I_4tUTl0aJKLACpmo3lcW5aDxkn2Mm0rPnj9TSjVurGtuzvHt97DkJvKPlIieEnMKVrcGncnMB1EKR-hhZUMFYZWYvnaEGoEZWU-vIYvcx5QwjRksoX6JhKqrnUeoH-n0efwGVocNGBFFyHb9wOcIK2Az-GPmY8JGiCH3GGHSTA3qUm9DuX_dS5hMtlHDMOEQ9uDPfnKTaQrvoQr_AAyU-ji9BPGfs-9dGlfwUuf-3r9vqv0FHrugyvD_sS_f765dfpWXXx49v56aeLygtCxrKuGVVlHGOokFw3gnHi6poDNxKMYqIxTotWsrXxkjbSqKZdC5DeGcGU4Uv0YdYdUv93gjzabcgeum7uzhZDuFbFmSV69wTc9FOKpTfLqKi10pwUiMyQT33OxS47pLAtw1lK7D4d-5COndMpJW8PutN6C81jwSGOArw_AMVc17XJRR_yI6c4U4zwwlUzF_IItw_vLv2xUnEl7Nnlyq70T_N59V1Zxe8AQPSt8g</recordid><startdate>20051201</startdate><enddate>20051201</enddate><creator>Weber, Thomas</creator><creator>Auer, Johann</creator><creator>O'Rourke, Michael F.</creator><creator>Kvas, Erich</creator><creator>Lassnig, Elisabeth</creator><creator>Lamm, Gudrun</creator><creator>Stark, Nina</creator><creator>Rammer, Martin</creator><creator>Eber, Bernd</creator><general>Oxford University Press</general><general>Oxford Publishing Limited (England)</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>K9.</scope><scope>7X8</scope></search><sort><creationdate>20051201</creationdate><title>Increased arterial wave reflections predict severe cardiovascular events in patients undergoing percutaneous coronary interventions</title><author>Weber, Thomas ; Auer, Johann ; O'Rourke, Michael F. ; Kvas, Erich ; Lassnig, Elisabeth ; Lamm, Gudrun ; Stark, Nina ; Rammer, Martin ; Eber, Bernd</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c500t-c5b2176689915638d5230a443e396e9725d9a85f62b9c61d697dfb5e6ca952793</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Aged</topic><topic>Angina Pectoris - diagnosis</topic><topic>Angina Pectoris - etiology</topic><topic>Angioplasty</topic><topic>Angioplasty, Balloon, Coronary</topic><topic>Arteries</topic><topic>Arteriosclerosis</topic><topic>Atherosclerosis (general aspects, experimental research)</topic><topic>Biological and medical sciences</topic><topic>Blood and lymphatic vessels</topic><topic>Blood Pressure - physiology</topic><topic>Cardiology. Vascular system</topic><topic>Coronary Angiography</topic><topic>Coronary Artery Disease - diagnosis</topic><topic>Coronary Artery Disease - physiopathology</topic><topic>Coronary Artery Disease - therapy</topic><topic>Coronary disease</topic><topic>Coronary heart disease</topic><topic>Coronary Stenosis - etiology</topic><topic>Female</topic><topic>Heart</topic><topic>Hemodynamics - physiology</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Myocardial Infarction - etiology</topic><topic>Predictive Value of Tests</topic><topic>Prognosis</topic><topic>Prospective Studies</topic><topic>Risk Factors</topic><topic>Wave reflections</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Weber, Thomas</creatorcontrib><creatorcontrib>Auer, Johann</creatorcontrib><creatorcontrib>O'Rourke, Michael F.</creatorcontrib><creatorcontrib>Kvas, Erich</creatorcontrib><creatorcontrib>Lassnig, Elisabeth</creatorcontrib><creatorcontrib>Lamm, Gudrun</creatorcontrib><creatorcontrib>Stark, Nina</creatorcontrib><creatorcontrib>Rammer, Martin</creatorcontrib><creatorcontrib>Eber, Bernd</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>MEDLINE - Academic</collection><jtitle>European heart journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Weber, Thomas</au><au>Auer, Johann</au><au>O'Rourke, Michael F.</au><au>Kvas, Erich</au><au>Lassnig, Elisabeth</au><au>Lamm, Gudrun</au><au>Stark, Nina</au><au>Rammer, Martin</au><au>Eber, Bernd</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Increased arterial wave reflections predict severe cardiovascular events in patients undergoing percutaneous coronary interventions</atitle><jtitle>European heart journal</jtitle><addtitle>Eur Heart J</addtitle><date>2005-12-01</date><risdate>2005</risdate><volume>26</volume><issue>24</issue><spage>2657</spage><epage>2663</epage><pages>2657-2663</pages><issn>0195-668X</issn><eissn>1522-9645</eissn><abstract>Aims Increased arterial wave reflections are associated with the presence and extent of coronary atherosclerosis and with cardiovascular mortality in selected populations. We prospectively evaluated their prognostic value in the short- and long-term following percutaneous coronary interventions (PCIs). Methods and results We non-invasively quantified wave reflections [expressed as augmentation index corrected for heart rate of 75 b.p.m. (AIx@75)] using applanation tonometry of the radial artery and a validated transfer function to obtain the corresponding aortic values in 262 patients undergoing PCI. During 2-year follow-up, 61 patients reached the primary endpoint [death, myocardial infarction (MI), and restenosis]. Increasing tertiles of Alx@75 were related to the rate of patients reaching the primary endpoint [15.2, 20 and 35.3%, respectively (P=0.001)], as well as the secondary endpoints total mortality, myocardial infarction and death plus myocardial infarction (RR for the third vs. the first tertile 4.33, 3.25 and 3.46, respectively, P<0.05). In a multivariable Cox-regression model, AIx@75 added prognostic value above and beyond clinical risk factors, angiographic variables, and medications (RR 1.8, 95%CI 1.18–2.76 per increasing AIx@75-tertile, P<0.01). Conclusion Increased arterial wave reflections are independently associated with an increased risk for severe short- and long-term cardiovascular events in patients undergoing PCI.</abstract><cop>Oxford</cop><pub>Oxford University Press</pub><pmid>16183688</pmid><doi>10.1093/eurheartj/ehi504</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0195-668X |
| ispartof | European heart journal, 2005-12, Vol.26 (24), p.2657-2663 |
| issn | 0195-668X 1522-9645 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_68838718 |
| source | Oxford University Press Journals All Titles (1996-Current); MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Aged Angina Pectoris - diagnosis Angina Pectoris - etiology Angioplasty Angioplasty, Balloon, Coronary Arteries Arteriosclerosis Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Blood Pressure - physiology Cardiology. Vascular system Coronary Angiography Coronary Artery Disease - diagnosis Coronary Artery Disease - physiopathology Coronary Artery Disease - therapy Coronary disease Coronary heart disease Coronary Stenosis - etiology Female Heart Hemodynamics - physiology Humans Male Medical sciences Middle Aged Myocardial Infarction - etiology Predictive Value of Tests Prognosis Prospective Studies Risk Factors Wave reflections |
| title | Increased arterial wave reflections predict severe cardiovascular events in patients undergoing percutaneous coronary interventions |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-21T21%3A53%3A24IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Increased%20arterial%20wave%20reflections%20predict%20severe%20cardiovascular%20events%20in%20patients%20undergoing%20percutaneous%20coronary%20interventions&rft.jtitle=European%20heart%20journal&rft.au=Weber,%20Thomas&rft.date=2005-12-01&rft.volume=26&rft.issue=24&rft.spage=2657&rft.epage=2663&rft.pages=2657-2663&rft.issn=0195-668X&rft.eissn=1522-9645&rft_id=info:doi/10.1093/eurheartj/ehi504&rft_dat=%3Cproquest_cross%3E943983401%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=215487830&rft_id=info:pmid/16183688&rfr_iscdi=true |