Mutations in DNA polymerase η are not detected in squamous cell carcinoma of the skin

The major etiological agent in skin cancer is exposure to UV‐irradiation and the concomitant DNA damage. UV‐induced DNA lesions, such as thymine dimers, block DNA synthesis by the major DNA polymerases and inhibit the progression of DNA replication. Bypass of thymine dimers and related lesions is de...

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