Galphaq-dependent signaling cascades stimulate water-seeking behavior

We used the mouse nephrin promoter to express a constitutively active Galphaq [Galphaq(Q>L)] transgene in mice. As previously reported, the transgene was expressed in kidney, pancreas, and brain, and the kidney phenotype was characterized by albuminuria and reduced nephron mass. Additional studie...

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Veröffentlicht in:	American journal of physiology. Renal physiology 2006-10, Vol.291 (4), p.F781-F789
Hauptverfasser:	Wang, Liming, Flannery, Patrick J, Athirakul, Krairerk, Dunn, Stephen R, Kourany, Wissam M, Spurney, Robert F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Feed Animals Diuresis DNA Primers Drinking Behavior GTP-Binding Protein alpha Subunits, Gq-G11 - genetics GTP-Binding Protein alpha Subunits, Gq-G11 - physiology Mice Mice, Transgenic Organ Specificity Reference Values Signal Transduction Systole Vasopressins - blood Water
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