Hyperglycemia and Outcome After Myocardial Infarction and Cardiac Surgery: So What?
Hyperglycemia is a frequent observation during acute illness such as myocardial infarction and after major surgery. The proportion of patients with hyperglycemia may be as high as 95% to 100% after cardiac surgery. This stress-induced hyperglycemia has a detrimental effect on outcome after myocardia...
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Veröffentlicht in: | Seminars in cardiothoracic and vascular anesthesia 2006-09, Vol.10 (3), p.220-223 |
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description | Hyperglycemia is a frequent observation during acute illness such as myocardial infarction and after major surgery. The proportion of patients with hyperglycemia may be as high as 95% to 100% after cardiac surgery. This stress-induced hyperglycemia has a detrimental effect on outcome after myocardial infarction and cardiac surgery. Mortality may increase by a factor of 4, especially in non-diabetic patients. Control of hyperglycemia to normalize blood glucose is associated with a clear clinical benefit. This effect is most beneficial in nondiabetic patients with hyperglycemia. The exact target level of glycemia is still a matter of investigation, but normalization to values between 80 and 125 mg/dL is probably optimal. |
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The exact target level of glycemia is still a matter of investigation, but normalization to values between 80 and 125 mg/dL is probably optimal.</description><identifier>ISSN: 1089-2532</identifier><identifier>EISSN: 1940-5596</identifier><identifier>DOI: 10.1177/1089253206291139</identifier><identifier>PMID: 16959754</identifier><language>eng</language><publisher>Thousand Oaks, CA: Sage Publications</publisher><subject>Cardiac Surgical Procedures - adverse effects ; Comorbidity ; Humans ; Hyperglycemia - drug therapy ; Hyperglycemia - epidemiology ; Hyperglycemia - etiology ; Insulin - therapeutic use ; Myocardial Infarction - drug therapy ; Myocardial Infarction - epidemiology ; Thoracic Surgery</subject><ispartof>Seminars in cardiothoracic and vascular anesthesia, 2006-09, Vol.10 (3), p.220-223</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c335t-cf704b3e771d209fcaad086aa1521cbdef1bc315bb2fc2ab2531fb9e5fa185423</citedby><cites>FETCH-LOGICAL-c335t-cf704b3e771d209fcaad086aa1521cbdef1bc315bb2fc2ab2531fb9e5fa185423</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/1089253206291139$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/1089253206291139$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,780,784,21819,27924,27925,43621,43622</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16959754$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hiesmayr, Michael J.</creatorcontrib><title>Hyperglycemia and Outcome After Myocardial Infarction and Cardiac Surgery: So What?</title><title>Seminars in cardiothoracic and vascular anesthesia</title><addtitle>Semin Cardiothorac Vasc Anesth</addtitle><description>Hyperglycemia is a frequent observation during acute illness such as myocardial infarction and after major surgery. The proportion of patients with hyperglycemia may be as high as 95% to 100% after cardiac surgery. This stress-induced hyperglycemia has a detrimental effect on outcome after myocardial infarction and cardiac surgery. Mortality may increase by a factor of 4, especially in non-diabetic patients. Control of hyperglycemia to normalize blood glucose is associated with a clear clinical benefit. This effect is most beneficial in nondiabetic patients with hyperglycemia. The exact target level of glycemia is still a matter of investigation, but normalization to values between 80 and 125 mg/dL is probably optimal.</description><subject>Cardiac Surgical Procedures - adverse effects</subject><subject>Comorbidity</subject><subject>Humans</subject><subject>Hyperglycemia - drug therapy</subject><subject>Hyperglycemia - epidemiology</subject><subject>Hyperglycemia - etiology</subject><subject>Insulin - therapeutic use</subject><subject>Myocardial Infarction - drug therapy</subject><subject>Myocardial Infarction - epidemiology</subject><subject>Thoracic Surgery</subject><issn>1089-2532</issn><issn>1940-5596</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kM9LwzAUx4Mobk7vniQnb9W8pGkbLzKGOmGywxSPJUmT2dE2M2kP_e_tfoAgeHqP9_28L3y_CF0DuQNI03sgmaCcUZJQAcDECRqDiEnEuUhOh32Qo50-QhchbAihhAI7RyNIBBcpj8doNe-3xq-rXpu6lFg2BV52rXa1wVPbGo_feqelL0pZ4dfGSq_b0jV7brY_a7zq_Nr4_gGvHP78ku3jJTqzsgrm6jgn6OP56X02jxbLl9fZdBFpxngbaZuSWDGTplBQIqyWsiBZIiVwCloVxoLSDLhS1Goq1RAErBKGWwkZjymboNuD79a7786ENq_LoE1Vyca4LuRJlrE4o2QAyQHU3oXgjc23vqyl73Mg-a7I_G-Rw8vN0btTtSl-H47NDUB0AIJcm3zjOt8MWf83_AG3b3rf</recordid><startdate>200609</startdate><enddate>200609</enddate><creator>Hiesmayr, Michael J.</creator><general>Sage Publications</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200609</creationdate><title>Hyperglycemia and Outcome After Myocardial Infarction and Cardiac Surgery: So What?</title><author>Hiesmayr, Michael J.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c335t-cf704b3e771d209fcaad086aa1521cbdef1bc315bb2fc2ab2531fb9e5fa185423</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Cardiac Surgical Procedures - adverse effects</topic><topic>Comorbidity</topic><topic>Humans</topic><topic>Hyperglycemia - drug therapy</topic><topic>Hyperglycemia - epidemiology</topic><topic>Hyperglycemia - etiology</topic><topic>Insulin - therapeutic use</topic><topic>Myocardial Infarction - drug therapy</topic><topic>Myocardial Infarction - epidemiology</topic><topic>Thoracic Surgery</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Hiesmayr, Michael J.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Seminars in cardiothoracic and vascular anesthesia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Hiesmayr, Michael J.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Hyperglycemia and Outcome After Myocardial Infarction and Cardiac Surgery: So What?</atitle><jtitle>Seminars in cardiothoracic and vascular anesthesia</jtitle><addtitle>Semin Cardiothorac Vasc Anesth</addtitle><date>2006-09</date><risdate>2006</risdate><volume>10</volume><issue>3</issue><spage>220</spage><epage>223</epage><pages>220-223</pages><issn>1089-2532</issn><eissn>1940-5596</eissn><abstract>Hyperglycemia is a frequent observation during acute illness such as myocardial infarction and after major surgery. The proportion of patients with hyperglycemia may be as high as 95% to 100% after cardiac surgery. This stress-induced hyperglycemia has a detrimental effect on outcome after myocardial infarction and cardiac surgery. Mortality may increase by a factor of 4, especially in non-diabetic patients. Control of hyperglycemia to normalize blood glucose is associated with a clear clinical benefit. This effect is most beneficial in nondiabetic patients with hyperglycemia. The exact target level of glycemia is still a matter of investigation, but normalization to values between 80 and 125 mg/dL is probably optimal.</abstract><cop>Thousand Oaks, CA</cop><pub>Sage Publications</pub><pmid>16959754</pmid><doi>10.1177/1089253206291139</doi><tpages>4</tpages></addata></record> |
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subjects | Cardiac Surgical Procedures - adverse effects Comorbidity Humans Hyperglycemia - drug therapy Hyperglycemia - epidemiology Hyperglycemia - etiology Insulin - therapeutic use Myocardial Infarction - drug therapy Myocardial Infarction - epidemiology Thoracic Surgery |
title | Hyperglycemia and Outcome After Myocardial Infarction and Cardiac Surgery: So What? |
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