Kinetic Resolution of Chiral Secondary Alcohols by Dehydrogenative Coupling with Recyclable Silicon-Stereogenic Silanes

Fishing for enantiomers: A novel kinetic resolution of racemic alcohols capable of two‐point binding makes use of silanes with silicon‐centered chirality. This strategy is based on a diastereoselective dehydrogenative silicon–oxygen coupling under copper catalysis (see scheme). The resolving silane...

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Veröffentlicht in:	Angewandte Chemie International Edition 2005-11, Vol.44 (46), p.7620-7624
Hauptverfasser:	Rendler, Sebastian, Auer, Gertrud, Oestreich, Martin
Format:	Artikel
Sprache:	eng
Schlagworte:	Alcohols - chemistry asymmetric catalysis Catalysis copper Copper - chemistry dehydrogenation Hydrogenation kinetic resolution Kinetics Ligands Molecular Conformation Molecular Structure Silanes - chemistry silicon Silicon - chemistry Stereoisomerism
Online-Zugang:	Volltext
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