Inhibition of matrix degrading enzymes and invasion in human glioblastoma (U87MG) Cells by isoflavones

Glioblastoma multiforme is a primary brain tumor associated with extensive invasion into surrounding brain tissue. Matrix metalloproteinases (MMPs) and urokinase plasminogen activation (uPA) system are shown to be involved in tumor invasion as they help in degradation of extracellular matrix (ECM) p...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of neuro-oncology 2006-09, Vol.79 (2), p.135-142
Hauptverfasser:	PULI, Shilpa, LAI, James C. K, BHUSHAN, Alok
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Brain Neoplasms - drug therapy Brain Neoplasms - enzymology Cell Line, Tumor Development. Senescence. Regeneration. Transplantation Dose-Response Relationship, Drug Down-Regulation Enzyme Inhibitors - administration & dosage Enzyme Precursors - drug effects Enzyme Precursors - metabolism Epidermal Growth Factor - metabolism Extracellular Matrix - metabolism Fundamental and applied biological sciences. Psychology Genistein - administration & dosage Glioblastoma - drug therapy Glioblastoma - enzymology Human viral diseases Humans Infectious diseases Matrix Metalloproteinase 2 - drug effects Matrix Metalloproteinase 2 - metabolism Matrix Metalloproteinase 9 - drug effects Matrix Metalloproteinase 9 - metabolism Matrix Metalloproteinases - drug effects Matrix Metalloproteinases - metabolism Matrix Metalloproteinases, Membrane-Associated Medical sciences Neoplasm Invasiveness Neurology Receptors, Cell Surface - drug effects Receptors, Cell Surface - metabolism Receptors, Urokinase Plasminogen Activator Vertebrates: nervous system and sense organs Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!