The Effects of Jatrophane Derivatives on the Reversion of MDR1- and MRP-mediated Multidrug Resistance in the MDA-MB-231 (HTB-26) Cell Line

Multidrug resistance (MDR) of cancer cells can be the result of a variety of mechanisms that are not completely understood. One of the most significant among them concerns altered membrane transport in tumor cells, often referred to as typical or classic MDR. This mechanism is related to the overexp...

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Veröffentlicht in:	Anticancer research 2005-11, Vol.25 (6B), p.4173-4178
Hauptverfasser:	FERREIRA, Maria-José U, GYEMANT, Nora, MADUREIRA, Ana Margarida, TANAKA, Masaru, KOOS, Kitti, DIDZIAPETRIS, Remigijus, MOLNAR, Joseph
Format:	Artikel
Sprache:	eng
Schlagworte:	ATP-Binding Cassette, Sub-Family B, Member 1 - antagonists & inhibitors ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism Biological and medical sciences Breast Neoplasms - drug therapy Breast Neoplasms - metabolism Cell Line, Tumor Diterpenes - pharmacology Drug Resistance, Multiple - drug effects Euphorbia - chemistry Fluoresceins - pharmacokinetics Humans Medical sciences Multidrug Resistance-Associated Proteins - antagonists & inhibitors Multidrug Resistance-Associated Proteins - metabolism Rhodamine 123 - pharmacokinetics Tumors
Online-Zugang:	Volltext
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