Influence of acute normovolaemic haemodilution on the dose–response relationship, time-course of action and pharmacokinetics of rocuronium bromide

Acute normovolaemic haemodilution (ANH) is an effective strategy for avoiding or reducing allogeneic blood transfusion. We aimed to study its effect on the pharmacological profile of rocuronium. In two study centres, 28 patients undergoing major surgery with ANH were matched with 28 control patients...

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Veröffentlicht in:	British journal of anaesthesia : BJA 2006-10, Vol.97 (4), p.482-488
Hauptverfasser:	Dahaba, A.A., Perelman, S.I., Moskowitz, D.M., Bennett, H.L., Shander, A., Oettl, K., Reibnegger, G., Metzler, H.
Format:	Artikel
Sprache:	eng
Schlagworte:	acute normovolaemic haemodilution Aged Androstanols - blood Androstanols - pharmacology Anesthesia Anesthesia, General Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences complications complications, acute normovolaemic haemodilution Dose-Response Relationship, Drug Female Half-Life Hemodilution Humans Intraoperative Care - methods Male Medical sciences Middle Aged neuromuscular block neuromuscular block, rocuronium Neuromuscular Junction - drug effects Neuromuscular Nondepolarizing Agents - blood Neuromuscular Nondepolarizing Agents - pharmacology Prospective Studies rocuronium
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