Correlation Among Pathology, Genotype, and Patient Outcomes in Glioblastoma

Glioblastomas are histologically and genetically heterogeneous. We have investigated to what extent histologic features reflect the genetic profile and whether they are predictive of clinical outcome. Key histologic characteristics, including major cell types (small cell, nonsmall cell), other compo...

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Veröffentlicht in:	Journal of neuropathology and experimental neurology 2006-09, Vol.65 (9), p.846-854
Hauptverfasser:	Homma, Taku, Fukushima, Takao, Vaccarella, Salvatore, Yonekawa, Yasuhiro, Di Patre, Pier Luigi, Franceschi, Silvia, Ohgaki, Hiroko
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Factors Antineoplastic agents Biological and medical sciences Brain Neoplasms - classification Brain Neoplasms - epidemiology Brain Neoplasms - genetics Brain Neoplasms - pathology Chemotherapy Chromosomes, Human, Pair 1 Chromosomes, Human, Pair 19 Community Health Planning Female Genes, erbB-1 - genetics Genotype Glioblastoma - classification Glioblastoma - epidemiology Glioblastoma - genetics Glioblastoma - pathology Human viral diseases Humans Infectious diseases Loss of Heterozygosity Male Medical sciences Middle Aged Multivariate Analysis Necrosis Neurology Pharmacology. Drug treatments PTEN Phosphohydrolase - genetics Sex Factors Statistics as Topic Switzerland - epidemiology Tumor Suppressor Protein p53 - genetics Viral diseases Viral diseases of the nervous system
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