Long-term results of children with acute myeloid leukemia: a report of three consecutive Phase III trials by the Children's Cancer Group: CCG 251, CCG 213 and CCG 2891

The Children's Cancer Group (CCG) conducted three Phase III prospective clinical trials for children with de novo acute myeloid leukemia between the years 1979 and 1995. A total of 1903 eligible children ages birth to 21 years of age were enrolled on CCG 251 ( n= 485), CCG 213 ( n= 532) and CCG...

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Veröffentlicht in:	Leukemia 2005-12, Vol.19 (12), p.2054-2062
Hauptverfasser:	Smith, F O, Alonzo, T A, Gerbing, R B, Woods, W G, Arceci, R J
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Acute myeloid leukemia Adolescent Adult Antineoplastic Combined Chemotherapy Protocols - therapeutic use Antineoplastic Protocols - standards Bone marrow Bone Marrow Transplantation Cancer Cancer Research Child Child, Preschool Children Children & youth Clinical trials Critical Care Medicine Cytarabine Daunomycin Dosage Dose-Response Relationship, Drug Female Follow-Up Studies Hematology Histocompatibility antigen HLA Humans Induction therapy Infant Infant, Newborn Intensive Internal Medicine Leukemia Leukemia, Myeloid - mortality Leukemia, Myeloid - therapy Male Medicine Medicine & Public Health Oncology original-manuscript Patients Remission Remission (Medicine) Remission Induction - methods Stem cell transplantation Survival Survival Analysis Transplantation
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