Potential scope of action of tissue kallikreins in CNS immune-mediated disease

The objective of this study was to define the potential scope of action of tissue kallikreins in T cell-mediated disease of the CNS. We demonstrate quantitatively the differential expression of all 15 human tissue kallikreins within brain, spinal cord and immune compartments. In human Jurkat T cells...

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Veröffentlicht in:	Journal of neuroimmunology 2006-09, Vol.178 (1), p.167-176
Hauptverfasser:	Scarisbrick, I.A., Blaber, S.I., Tingling, J.T., Rodriguez, M., Blaber, M., Christophi, G.P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Bone Marrow - immunology Bone Marrow - metabolism Brain - immunology Brain - metabolism Demyelinating Autoimmune Diseases, CNS - immunology Demyelinating Autoimmune Diseases, CNS - metabolism Enzyme Hormones - pharmacology Humans Inflammation Jurkat cell Lymphocyte Activation - immunology Lymphocytes - immunology Lymphocytes - metabolism Multiple sclerosis Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - analysis Serine protease Spinal Cord - immunology Spinal Cord - metabolism Spleen - immunology Spleen - metabolism Steroid hormone Steroids - pharmacology Thymus Gland - immunology Thymus Gland - metabolism Tissue Kallikreins - biosynthesis Tissue Kallikreins - drug effects Tissue Kallikreins - immunology
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