Transfer of Endothelial Progenitor and Bone Marrow Cells Influences Atherosclerotic Plaque Size and Composition in Apolipoprotein E Knockout Mice

OBJECTIVES—Recent clinical trials use cell therapy with bone marrow (BM) cells or endothelial progenitor cells (EPCs) for ischemic syndromes. We explored the effect of BM cell– or spleen cell–derived EPC transfer on plaque size and stability markers in the apolipoprotein E knockout (apoE KO) mouse m...

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Veröffentlicht in:	Arteriosclerosis, thrombosis, and vascular biology thrombosis, and vascular biology, 2005-12, Vol.25 (12), p.2636-2641
Hauptverfasser:	George, Jacob, Afek, Arnon, Abashidze, Anastasia, Shmilovich, Haim, Deutsch, Varda, Kopolovich, Juri, Miller, Hylton, Keren, Gad
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies - blood Apolipoproteins E - genetics Atherosclerosis (general aspects, experimental research) Atherosclerosis - immunology Atherosclerosis - pathology Atherosclerosis - therapy Biological and medical sciences Biomarkers Blood and lymphatic vessels Blood vessels and receptors Bone Marrow Transplantation Cardiology. Vascular system Coronary heart disease Cytokines - blood Cytokines - genetics Disease Models, Animal Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Endothelium, Vascular - pathology Fundamental and applied biological sciences. Psychology Heart Lipoproteins, LDL - immunology Liver - cytology Lung - cytology Male Medical sciences Mice Mice, Knockout RNA, Messenger - analysis Sinus of Valsalva - pathology Sinus of Valsalva - physiopathology Spleen - cytology Stem Cell Transplantation Vertebrates: cardiovascular system
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