Cytotoxic labdane alkaloids from an ascidian Lissoclinum sp.: Isolation, structure elucidation, and structure–activity relationship

Four new cytotoxic labdane alkaloids, haterumaimides N–Q were isolated from the ascidian Lissoclinum sp. Their structures and SAR studies of this series of alkaloids are described. Four labdane alkaloids, haterumaimides N–Q ( 1– 4), were isolated from an ascidian Lissoclinum sp. and their structures...

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