Mechanisms of Increased Vascular Superoxide Production in an Experimental Model of Idiopathic Dilated Cardiomyopathy

OBJECTIVE—In the present study, we sought to identify mechanisms underlying increased oxidative stress in vascular tissue in an experimental animal model of chronic congestive heart failure (CHF). METHODS AND RESULTS—Superoxide and nitric oxide (NO) was measured in vessels from cardiomyopathic hamst...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Arteriosclerosis, thrombosis, and vascular biology thrombosis, and vascular biology, 2005-12, Vol.25 (12), p.2554-2559
Hauptverfasser:	Mollnau, Hanke, Oelze, Matthias, August, Michael, Wendt, Maria, Daiber, Andreas, Schulz, Eberhard, Baldus, Stephan, Kleschyov, Andrei L, Materne, Anke, Wenzel, Philip, Hink, Ulrich, Nickenig, Georg, Fleming, Ingrid, Münzel, Thomas
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiotensin-Converting Enzyme Inhibitors - pharmacology Animals Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Blood coagulation. Blood cells Body Weight Captopril - pharmacology Cardiology. Vascular system Cardiomyopathy, Dilated - drug therapy Cardiomyopathy, Dilated - metabolism Cardiomyopathy, Dilated - pathology Cardiovascular system Cell Adhesion Molecules - metabolism Cricetinae Disease Models, Animal Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Female Fundamental and applied biological sciences. Psychology Guanylate Cyclase Heart Failure - drug therapy Heart Failure - metabolism Heart Failure - pathology Male Medical sciences Mesocricetus Microfilament Proteins - metabolism Miscellaneous Molecular and cellular biology Myocardium - metabolism Myocardium - pathology NADPH Oxidases - metabolism Nitric Oxide - metabolism Nitric Oxide Synthase Type III - metabolism Organ Size Oxidative Stress - physiology Pharmacology. Drug treatments Phosphoproteins - metabolism Platelet Receptors, Cytoplasmic and Nuclear - metabolism Renin-Angiotensin System - physiology Soluble Guanylyl Cyclase Superoxides - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!