Pyruvate Improves Neutrophilic Nitric Oxide Generation in Peritoneal Dialysis Solutions

: To investigate the effects of pyruvate (Pyr)‐based peritoneal dialysis solutions (P‐PDS) on neutrophilic nitric oxide (NO) generation, we incubated human peripheral neutrophils in dL‐lactate (Lac, 40 mM)‐based PDS and equimolar P‐PDS, and Hanks’ balanced salt solution at various pH and high gluco...

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Veröffentlicht in:	Artificial organs 2005-12, Vol.29 (12), p.976-980
Hauptverfasser:	Wu, Yi-Tai, Wu, Zhao-Long, Jiang, Xiao-Feng, Li, Su, Zhou, Fang-Qiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Acidosis Cell Survival Cells, Cultured Dialysis Solutions - pharmacology Glucose Glucose - pharmacology Humans Hydride Hydrogen-Ion Concentration Lactate Lactates - pharmacology Neutrophils - metabolism Nitric oxide Nitric Oxide - biosynthesis Peritoneal Dialysis Peritoneal dialysis solutions Pyruvate Pyruvic Acid - pharmacology Redox status Sorbitol pathway Spectrophotometry Zymosan
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