Prohibitin and cofilin are intracellular effectors of transforming growth factor β signaling in human prostate cancer cells

A proteomic analysis was pursued to identify new signaling effectors of transforming growth factor beta1 (TGF-beta1) that serve as potential intracellular effectors of its apoptotic action in human prostate cancer cells. The androgen-sensitive and TGF-beta-responsive human prostate cancer cells, LNC...

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Veröffentlicht in:	Cancer research (Chicago, Ill.) Ill.), 2006-09, Vol.66 (17), p.8640-8647
Hauptverfasser:	BEIBEI ZHU, FUKADA, Kei, HAINING ZHU, KYPRIANOU, Natasha
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cell Line, Tumor Cell physiology Cell Survival - drug effects Cofilin 1 - physiology Cytochromes c - metabolism Dihydrotestosterone - pharmacology Fundamental and applied biological sciences. Psychology Gynecology. Andrology. Obstetrics Humans Hydrogen-Ion Concentration Male Male genital diseases Medical sciences Molecular and cellular biology Nephrology. Urinary tract diseases Prostatic Neoplasms - physiopathology Proteome Repressor Proteins - physiology Signal Transduction Transforming Growth Factor beta - pharmacology Transforming Growth Factor beta - physiology Tumors Tumors of the urinary system Urinary tract. Prostate gland
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