Differential Expression of Neuronal Genes Defines Subtypes of Disseminated Neuroblastoma with Favorable and Unfavorable Outcome

Purpose: Identification of molecular characteristics of spontaneously regressing stage IVS and progressing stage IV neuroblastoma to improve discrimination of patients with metastatic disease following favorable and unfavorable clinical courses. Experimental Design: Serial analysis of gene expressio...

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Veröffentlicht in:	Clinical cancer research 2006-09, Vol.12 (17), p.5118-5128
Hauptverfasser:	FISCHER, Matthias, OBERTHUER, André, BRORS, Benedikt, KAHLERT, Yvonne, SKOWRON, Matthias, VOTH, Harald, WARNAT, Patrick, ERNESTUS, Karen, HERO, Barbara, BERTHOLD, Frank
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic agents Biological and medical sciences Child, Preschool Disease Progression Follow-Up Studies Gene Expression Profiling gene signature Humans Infant Kaplan-Meier Estimate Medical sciences Neoplasm Staging neuroblastoma Neuroblastoma - diagnosis Neuroblastoma - genetics Neuroblastoma - therapy Neurology neuronal differentiation Oligonucleotide Array Sequence Analysis - methods outcome prediction Pharmacology. Drug treatments Reverse Transcriptase Polymerase Chain Reaction - methods Survival Rate Transcription, Genetic - genetics Tumors of the nervous system. Phacomatoses
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