Olfactory Receptor Sequence Polymorphism Within and Between Breeds of Dogs
Olfactory receptors, to which odorant molecules specifically bind, are encoded by the largest gene family yet identified in the mammalian genome. We investigated additional polymorphism due to the possible existence of multiple alleles dispersed in different dog breeds by carrying out a survey of th...
Gespeichert in:
| Veröffentlicht in: | The Journal of heredity 2005-11, Vol.96 (7), p.812-816 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 816 |
|---|---|
| container_issue | 7 |
| container_start_page | 812 |
| container_title | The Journal of heredity |
| container_volume | 96 |
| creator | Tacher, Sandrine Quignon, Pascale Rimbault, Maud Dreano, Stephane Andre, Catherine Galibert, Francis |
| description | Olfactory receptors, to which odorant molecules specifically bind, are encoded by the largest gene family yet identified in the mammalian genome. We investigated additional polymorphism due to the possible existence of multiple alleles dispersed in different dog breeds by carrying out a survey of the sequences of 16 olfactory receptor genes in a sample of 95 dogs of 20 different breeds. The level of polymorphism was high--all genes were found to have allelic variants--leading to amino acid changes and pseudogenization of some alleles in a number of cases. This preliminary study also revealed that some alleles are breed specific (or rare in the dog population), with some representing the major allele in the breeds concerned. |
| doi_str_mv | 10.1093/jhered/esi113 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_68816951</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>947104171</sourcerecordid><originalsourceid>FETCH-LOGICAL-c450t-b5e50b3cb55b82e12bb304290d5e2cc3a901bb5c739030b192f49ff2b210f42a3</originalsourceid><addsrcrecordid>eNqF0Utv1DAUBWALUdGhsGQLFgt2ae-14yRe0vJoUVFR32Jj2Z6bTqZJPNgZwfz7psqoSGzY2Jb96cj2YewNwj6ClgfLBUWaH1BqEOUzNsO8UFkppXzOZgBCZKhA7rKXKS0BAJWGF2wXC6FQoZ6xb2dtbf0Q4oafk6fVuOIX9GtNvSf-I7SbLsTVokkdv2mGRdNz28_5IQ2_iXp-GInmiYeafwp36RXbqW2b6PV23mNXXz5fHh1np2dfT44-nmY-VzBkTpECJ71TylWCUDgnIRca5oqE99JqQOeUL6UGCQ61qHNd18IJhDoXVu6xD1PuKobxomkwXZM8ta3tKayTKaoKC63wvxC1LHWu9Ajf_wOXYR378RGjqaAah0eUTcjHkFKk2qxi09m4MQjmsQozVWGmKkb_dhu6dt24_aS3f_83sEkD_Xk6t_HeFKUslTm-_Wmuz2-vC7i8Md9H_27ytQ3G3sUmmasLASgBIUcBhXwAqiedsw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>198081989</pqid></control><display><type>article</type><title>Olfactory Receptor Sequence Polymorphism Within and Between Breeds of Dogs</title><source>Oxford University Press Journals</source><source>MEDLINE</source><source>Free E-Journal (出版社公開部分のみ）</source><creator>Tacher, Sandrine ; Quignon, Pascale ; Rimbault, Maud ; Dreano, Stephane ; Andre, Catherine ; Galibert, Francis</creator><creatorcontrib>Tacher, Sandrine ; Quignon, Pascale ; Rimbault, Maud ; Dreano, Stephane ; Andre, Catherine ; Galibert, Francis</creatorcontrib><description>Olfactory receptors, to which odorant molecules specifically bind, are encoded by the largest gene family yet identified in the mammalian genome. We investigated additional polymorphism due to the possible existence of multiple alleles dispersed in different dog breeds by carrying out a survey of the sequences of 16 olfactory receptor genes in a sample of 95 dogs of 20 different breeds. The level of polymorphism was high--all genes were found to have allelic variants--leading to amino acid changes and pseudogenization of some alleles in a number of cases. This preliminary study also revealed that some alleles are breed specific (or rare in the dog population), with some representing the major allele in the breeds concerned.</description><identifier>ISSN: 0022-1503</identifier><identifier>EISSN: 1465-7333</identifier><identifier>DOI: 10.1093/jhered/esi113</identifier><identifier>PMID: 16251519</identifier><identifier>CODEN: JOHEA8</identifier><language>eng</language><publisher>United States: Oxford University Press</publisher><subject>alleles ; Amino Acid Substitution - genetics ; Animals ; Breeding ; Canis ; dog breeds ; Dogs ; Dogs - genetics ; Gene Frequency ; Genes ; olfactory receptors ; Polymerase Chain Reaction - methods ; Polymorphism ; Polymorphism, Single Nucleotide - genetics ; Receptors, Odorant - genetics ; Sequence Analysis, DNA - methods ; single nucleotide polymorphism ; Smell</subject><ispartof>The Journal of heredity, 2005-11, Vol.96 (7), p.812-816</ispartof><rights>Copyright Oxford University Press(England) Nov 2005</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c450t-b5e50b3cb55b82e12bb304290d5e2cc3a901bb5c739030b192f49ff2b210f42a3</citedby><cites>FETCH-LOGICAL-c450t-b5e50b3cb55b82e12bb304290d5e2cc3a901bb5c739030b192f49ff2b210f42a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16251519$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tacher, Sandrine</creatorcontrib><creatorcontrib>Quignon, Pascale</creatorcontrib><creatorcontrib>Rimbault, Maud</creatorcontrib><creatorcontrib>Dreano, Stephane</creatorcontrib><creatorcontrib>Andre, Catherine</creatorcontrib><creatorcontrib>Galibert, Francis</creatorcontrib><title>Olfactory Receptor Sequence Polymorphism Within and Between Breeds of Dogs</title><title>The Journal of heredity</title><addtitle>J Hered</addtitle><description>Olfactory receptors, to which odorant molecules specifically bind, are encoded by the largest gene family yet identified in the mammalian genome. We investigated additional polymorphism due to the possible existence of multiple alleles dispersed in different dog breeds by carrying out a survey of the sequences of 16 olfactory receptor genes in a sample of 95 dogs of 20 different breeds. The level of polymorphism was high--all genes were found to have allelic variants--leading to amino acid changes and pseudogenization of some alleles in a number of cases. This preliminary study also revealed that some alleles are breed specific (or rare in the dog population), with some representing the major allele in the breeds concerned.</description><subject>alleles</subject><subject>Amino Acid Substitution - genetics</subject><subject>Animals</subject><subject>Breeding</subject><subject>Canis</subject><subject>dog breeds</subject><subject>Dogs</subject><subject>Dogs - genetics</subject><subject>Gene Frequency</subject><subject>Genes</subject><subject>olfactory receptors</subject><subject>Polymerase Chain Reaction - methods</subject><subject>Polymorphism</subject><subject>Polymorphism, Single Nucleotide - genetics</subject><subject>Receptors, Odorant - genetics</subject><subject>Sequence Analysis, DNA - methods</subject><subject>single nucleotide polymorphism</subject><subject>Smell</subject><issn>0022-1503</issn><issn>1465-7333</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqF0Utv1DAUBWALUdGhsGQLFgt2ae-14yRe0vJoUVFR32Jj2Z6bTqZJPNgZwfz7psqoSGzY2Jb96cj2YewNwj6ClgfLBUWaH1BqEOUzNsO8UFkppXzOZgBCZKhA7rKXKS0BAJWGF2wXC6FQoZ6xb2dtbf0Q4oafk6fVuOIX9GtNvSf-I7SbLsTVokkdv2mGRdNz28_5IQ2_iXp-GInmiYeafwp36RXbqW2b6PV23mNXXz5fHh1np2dfT44-nmY-VzBkTpECJ71TylWCUDgnIRca5oqE99JqQOeUL6UGCQ61qHNd18IJhDoXVu6xD1PuKobxomkwXZM8ta3tKayTKaoKC63wvxC1LHWu9Ajf_wOXYR378RGjqaAah0eUTcjHkFKk2qxi09m4MQjmsQozVWGmKkb_dhu6dt24_aS3f_83sEkD_Xk6t_HeFKUslTm-_Wmuz2-vC7i8Md9H_27ytQ3G3sUmmasLASgBIUcBhXwAqiedsw</recordid><startdate>20051101</startdate><enddate>20051101</enddate><creator>Tacher, Sandrine</creator><creator>Quignon, Pascale</creator><creator>Rimbault, Maud</creator><creator>Dreano, Stephane</creator><creator>Andre, Catherine</creator><creator>Galibert, Francis</creator><general>Oxford University Press</general><general>Oxford Publishing Limited (England)</general><scope>FBQ</scope><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QG</scope><scope>7SN</scope><scope>7SS</scope><scope>7TK</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>K9.</scope><scope>P64</scope><scope>RC3</scope><scope>7QR</scope><scope>7X8</scope></search><sort><creationdate>20051101</creationdate><title>Olfactory Receptor Sequence Polymorphism Within and Between Breeds of Dogs</title><author>Tacher, Sandrine ; Quignon, Pascale ; Rimbault, Maud ; Dreano, Stephane ; Andre, Catherine ; Galibert, Francis</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c450t-b5e50b3cb55b82e12bb304290d5e2cc3a901bb5c739030b192f49ff2b210f42a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>alleles</topic><topic>Amino Acid Substitution - genetics</topic><topic>Animals</topic><topic>Breeding</topic><topic>Canis</topic><topic>dog breeds</topic><topic>Dogs</topic><topic>Dogs - genetics</topic><topic>Gene Frequency</topic><topic>Genes</topic><topic>olfactory receptors</topic><topic>Polymerase Chain Reaction - methods</topic><topic>Polymorphism</topic><topic>Polymorphism, Single Nucleotide - genetics</topic><topic>Receptors, Odorant - genetics</topic><topic>Sequence Analysis, DNA - methods</topic><topic>single nucleotide polymorphism</topic><topic>Smell</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tacher, Sandrine</creatorcontrib><creatorcontrib>Quignon, Pascale</creatorcontrib><creatorcontrib>Rimbault, Maud</creatorcontrib><creatorcontrib>Dreano, Stephane</creatorcontrib><creatorcontrib>Andre, Catherine</creatorcontrib><creatorcontrib>Galibert, Francis</creatorcontrib><collection>AGRIS</collection><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Animal Behavior Abstracts</collection><collection>Ecology Abstracts</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Neurosciences Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>The Journal of heredity</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tacher, Sandrine</au><au>Quignon, Pascale</au><au>Rimbault, Maud</au><au>Dreano, Stephane</au><au>Andre, Catherine</au><au>Galibert, Francis</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Olfactory Receptor Sequence Polymorphism Within and Between Breeds of Dogs</atitle><jtitle>The Journal of heredity</jtitle><addtitle>J Hered</addtitle><date>2005-11-01</date><risdate>2005</risdate><volume>96</volume><issue>7</issue><spage>812</spage><epage>816</epage><pages>812-816</pages><issn>0022-1503</issn><eissn>1465-7333</eissn><coden>JOHEA8</coden><abstract>Olfactory receptors, to which odorant molecules specifically bind, are encoded by the largest gene family yet identified in the mammalian genome. We investigated additional polymorphism due to the possible existence of multiple alleles dispersed in different dog breeds by carrying out a survey of the sequences of 16 olfactory receptor genes in a sample of 95 dogs of 20 different breeds. The level of polymorphism was high--all genes were found to have allelic variants--leading to amino acid changes and pseudogenization of some alleles in a number of cases. This preliminary study also revealed that some alleles are breed specific (or rare in the dog population), with some representing the major allele in the breeds concerned.</abstract><cop>United States</cop><pub>Oxford University Press</pub><pmid>16251519</pmid><doi>10.1093/jhered/esi113</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0022-1503 |
| ispartof | The Journal of heredity, 2005-11, Vol.96 (7), p.812-816 |
| issn | 0022-1503 1465-7333 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_68816951 |
| source | Oxford University Press Journals; MEDLINE; Free E-Journal (出版社公開部分のみ） |
| subjects | alleles Amino Acid Substitution - genetics Animals Breeding Canis dog breeds Dogs Dogs - genetics Gene Frequency Genes olfactory receptors Polymerase Chain Reaction - methods Polymorphism Polymorphism, Single Nucleotide - genetics Receptors, Odorant - genetics Sequence Analysis, DNA - methods single nucleotide polymorphism Smell |
| title | Olfactory Receptor Sequence Polymorphism Within and Between Breeds of Dogs |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-01T11%3A16%3A09IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Olfactory%20Receptor%20Sequence%20Polymorphism%20Within%20and%20Between%20Breeds%20of%20Dogs&rft.jtitle=The%20Journal%20of%20heredity&rft.au=Tacher,%20Sandrine&rft.date=2005-11-01&rft.volume=96&rft.issue=7&rft.spage=812&rft.epage=816&rft.pages=812-816&rft.issn=0022-1503&rft.eissn=1465-7333&rft.coden=JOHEA8&rft_id=info:doi/10.1093/jhered/esi113&rft_dat=%3Cproquest_cross%3E947104171%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=198081989&rft_id=info:pmid/16251519&rfr_iscdi=true |