The genetic background of uremic secondary hyperparathyroidism

Many studies have shown how gene mutations and genetic polymorphisms could influence secondary uremic hyperparathyroidism (HPTH), modulating parathyroid (PT) function and hyperplasia. Parathyroid hormone (PTH) gene expression and hormone secretion is regulated mainly by serum calcium, with a post-tr...

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Veröffentlicht in:	Journal of nephrology 2005-09, Vol.18 (5), p.537-547
Hauptverfasser:	Aucella, Filippo, Morrone, Luigi, Stallone, Carmine, Gesualdo, Loreto
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Proliferation Gene Expression Regulation Genetic Therapy Humans Hyperparathyroidism, Secondary - genetics Hyperparathyroidism, Secondary - therapy Kidney Failure, Chronic - genetics Mutation Parathyroid Glands - cytology Parathyroid Hormone - biosynthesis Parathyroid Hormone - secretion Polymorphism, Genetic Receptors, Calcitriol - genetics Receptors, Calcium-Sensing - genetics Uremia - genetics
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