Microarray Analysis of LIF/Stat3 Transcriptional Targets in Embryonic Stem Cells

Mouse embryonic stem (ES) cells can be propagated in vitro while retaining their properties of pluripotency and self‐renewal under the continuous presence of leukemia inhibitor factor (LIF). An essential role has been attributed to subsequent activation of the Stat3 transcription factor in mediating...

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Veröffentlicht in:	Stem cells (Dayton, Ohio) Ohio), 2005-11, Vol.23 (10), p.1634-1642
Hauptverfasser:	Sekkaï, Dalila, Gruel, Gaëtan, Herry, Magali, Moucadel, Virginie, Constantinescu, Stefan N., Albagli, Olivier, Roux, Diana Tronik‐Le, Vainchenker, William, Bennaceur‐Griscelli, Annelise
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Differentiation Cell Line Down-Regulation Embryo Research Gene Expression Regulation grg5 Interleukin-6 - genetics Interleukin-6 - metabolism Kv1.2 Potassium Channel Leukemia inhibitor factor Leukemia Inhibitory Factor Mice Microarray Microarray Analysis Mutation Promoter Regions, Genetic Reverse Transcriptase Polymerase Chain Reaction Self‐renewal Stat3 STAT3 Transcription Factor - genetics STAT3 Transcription Factor - metabolism Stem Cells - cytology Time Factors Transcription Factors - metabolism Up-Regulation
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