ADAM12 is highly expressed in carcinoma-associated stroma and is required for mouse prostate tumor progression

The interaction between stromal cells and tumor cells is emerging as a critical aspect of tumor progression. Yet there is a paucity of molecular markers for cells participating in such interactions, and only few genes are known to play a critical role in this process. Here, we describe the identific...

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Veröffentlicht in:	Oncogene 2006-08, Vol.25 (39), p.5462-5466
Hauptverfasser:	Peduto, L, Reuter, V E, Sehara-Fujisawa, A, Shaffer, D R, Scher, H I, Blobel, C P
Format:	Artikel
Sprache:	eng
Schlagworte:	ADAM Proteins - genetics ADAM12 Protein Animal models Animals Antineoplastic Agents - pharmacology Apoptosis Biological and medical sciences Breast cancer Cell Biology Cell Division - drug effects Cell growth Cell physiology Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes Colon cancer Disease Progression Drug development Female Fundamental and applied biological sciences. Psychology Gene Expression Regulation, Neoplastic Genetic markers Genetics Gynecology. Andrology. Obstetrics Human Genetics Internal Medicine Intestinal Neoplasms - genetics Male Male genital diseases Mammary Neoplasms, Animal - genetics Medical sciences Medicine Medicine & Public Health Metalloproteinase Mice Molecular and cellular biology Nephrology. Urinary tract diseases Oncology Prostate cancer Prostatic Neoplasms - pathology Rodents short-communication Stromal cells Stromal Cells - pathology Tumor cells Tumors Tumors of the urinary system Urinary tract. Prostate gland
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