Do Recipients of Kidneys From Donors Treated With Streptokinase Develop Anti-streptokinase Antibodies?

Streptokinase is used for preflush for non–heart-beating donors (NHBDs) in our center. The aim of this study was to evaluate whether the use of thrombolytic streptokinase results in the production of anti-streptokinase antibodies in the recipients after renal transplantation. Recipient sera taken pr...

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Veröffentlicht in:Transplantation proceedings 2005-10, Vol.37 (8), p.3272-3273
Hauptverfasser: Mi, H., Gupta, A., Gok, M.A., Asher, J., Shenton, B.K., Stamp, S., Carter, V., Martin, J. Del Rio, Soomro, N.A., Jaques, B.C., Manas, D.M., Talbot, D.
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container_end_page 3273
container_issue 8
container_start_page 3272
container_title Transplantation proceedings
container_volume 37
creator Mi, H.
Gupta, A.
Gok, M.A.
Asher, J.
Shenton, B.K.
Stamp, S.
Carter, V.
Martin, J. Del Rio
Soomro, N.A.
Jaques, B.C.
Manas, D.M.
Talbot, D.
description Streptokinase is used for preflush for non–heart-beating donors (NHBDs) in our center. The aim of this study was to evaluate whether the use of thrombolytic streptokinase results in the production of anti-streptokinase antibodies in the recipients after renal transplantation. Recipient sera taken prior to and at 1 and 6 months posttransplant were tested for the presence of antibodies to streptokinase using an enzyme-linked immunosorbent assay assay. No differences were detected between a group of 18 recipients who had kidneys from thrombolytic-treated NHBDs and a further group of 18 who received NHBD kidneys without such treatment.
doi_str_mv 10.1016/j.transproceed.2005.09.035
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subjects Antibodies - blood
Antibody Formation
Biological and medical sciences
Fibrinolytic Agents - therapeutic use
Fundamental and applied biological sciences. Psychology
Fundamental immunology
Heart Arrest
Humans
Kidney Transplantation - immunology
Medical sciences
Retrospective Studies
Streptokinase - immunology
Streptokinase - therapeutic use
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Tissue Donors
Tissue, organ and graft immunology
title Do Recipients of Kidneys From Donors Treated With Streptokinase Develop Anti-streptokinase Antibodies?
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