Induction of IL‐6 release from human T cells by PAR‐1 and PAR‐2 agonists

Proteinase‐activated receptors (PAR) have been recognized as playing an important role in inflammation and immune response. However, little is known of the expression and function of PAR on human T cells. In this study, the expression of PAR on highly purified human T cells was determined and the se...

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Veröffentlicht in:	Immunology and cell biology 2006-10, Vol.84 (5), p.461-466
Hauptverfasser:	Li, Tao, He, Shaoheng
Format:	Artikel
Sprache:	eng
Schlagworte:	Cell Separation Humans IL‐6 Inflammation - immunology Interleukin-6 - immunology Interleukin-6 - metabolism Peptides - pharmacology proteinase‐activated receptor Receptors, Proteinase-Activated - agonists Receptors, Proteinase-Activated - antagonists & inhibitors Receptors, Proteinase-Activated - metabolism Serine Endopeptidases - metabolism Serine Proteinase Inhibitors - pharmacology T cell T-Lymphocytes - cytology T-Lymphocytes - drug effects T-Lymphocytes - immunology T-Lymphocytes - metabolism thrombin trypsin tryptase
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