Prophylactic Bilateral Salpingo-Oophorectomy Compared With Surveillance in Women With BRCA Mutations

OBJECTIVE:The objective of this study was to evaluate clinical factors associated with choosing prophylactic bilateral salpingo-oophorectomy (BSO) over surveillance in women with a BRCA1 or BRCA2 mutation. METHODS:Between 1996 and 2005, 139 women who tested positive for a BRCA1 or BRCA2 mutation wer...

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Veröffentlicht in:	Obstetrics and gynecology (New York. 1953) 2006-09, Vol.108 (3, Part 1), p.515-520
Hauptverfasser:	Schmeler, Kathleen M., Sun, Charlotte C., Bodurka, Diane C., White, Kristin G., Soliman, Pamela T., Uyei, Anne R., Erlichman, Julie L., Arun, Banu K., Daniels, Molly S., Rimes, Susan A., Peterson, Susan K., Slomovitz, Brian M., Milam, Michael R., Gershenson, David M., Lu, Karen H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Factors Aged Biological and medical sciences Breast Neoplasms - epidemiology Breast Neoplasms - genetics Breast Neoplasms - prevention & control Chemotherapy, Adjuvant Cohort Studies Fallopian Tube Neoplasms - genetics Fallopian Tube Neoplasms - prevention & control Fallopian Tube Neoplasms - surgery Female Female genital diseases Genes, BRCA1 Genes, BRCA2 Gynecology. Andrology. Obstetrics Humans Hysterectomy Mastectomy Medical sciences Middle Aged Mutation Ovarian Neoplasms - genetics Ovarian Neoplasms - prevention & control Ovarian Neoplasms - surgery Ovariectomy Parity Pregnancy Salpingostomy - methods Time Factors Tumors
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