Telomere Shortening and Mood Disorders: Preliminary Support for a Chronic Stress Model of Accelerated Aging

Little is known about the biological mechanisms underlying the excess medical morbidity and mortality associated with mood disorders. Substantial evidence supports abnormalities in stress-related biological systems in depression. Accelerated telomere shortening may reflect stress-related oxidative d...

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Veröffentlicht in:	Biological psychiatry (1969) 2006-09, Vol.60 (5), p.432-435
Hauptverfasser:	Simon, Naomi M., Smoller, Jordan W., McNamara, Kate L., Maser, Richard S., Zalta, Alyson K., Pollack, Mark H., Nierenberg, Andrew A., Fava, Maurizio, Wong, Kwok-Kin
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adult and adolescent clinical studies Aging Aging - genetics Anxiety - complications Anxiety - genetics Biological and medical sciences bipolar Bipolar Disorder - complications Bipolar Disorder - genetics Case-Control Studies Cellular Senescence - genetics Chromosome Breakage Chronic Disease Depression Female Humans major depressive disorder Male Matched-Pair Analysis Medical sciences Middle Aged Models, Genetic mood disorder Mood disorders Mood Disorders - complications Mood Disorders - genetics Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Reference Values Statistics, Nonparametric stress Stress, Psychological - etiology Stress, Psychological - genetics Telomere
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