PLASMODIUM VIVAX: TRANSMISSION-BLOCKING IMMUNITY IN A MALARIA-ENDEMIC AREA OF COLOMBIA
Plasmodium vivax transmission-blocking activity was assessed in sera from acutely infected patients from a malaria-endemic area in Colombia. We measured reduction in the number of oocysts that developed in the midguts of Anopheles albimanus mosquitoes artificially fed with blood from these patients....
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| Veröffentlicht in: | The American journal of tropical medicine and hygiene 2005-11, Vol.73 (5 suppl), p.38-43 |
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| container_issue | 5 suppl |
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| container_title | The American journal of tropical medicine and hygiene |
| container_volume | 73 |
| creator | AREVALO-HERRERA, MYRIAM SOLARTE, YEZID ZAMORA, FELIPE MENDEZ, FABIAN YASNOT, MARIA FERNANDA ROCHA, LEONARDO LONG, CAROLE MILLER, LOUIS H HERRERA, SOCRATES |
| description | Plasmodium vivax transmission-blocking activity was assessed in sera from acutely infected patients from a malaria-endemic area in Colombia. We measured reduction in the number of oocysts that developed in the midguts of Anopheles albimanus mosquitoes artificially fed with blood from these patients. Of 88 mosquito batches that developed infections when parasites were mixed with normal AB human serum, one-third (36.4%) showed full transmission-blocking activity (>or= 90% inhibition) when mixed with autologous sera, 29.6% showed partial activity (50-89%), 17.0% did not block transmission (0-50%), and 17% did not enhance transmission. Transmission-blocking activity correlated with antibody titer by an immunofluorescent antibody test and decreased with the serial dilution of the sera. This activity disappeared at a 1:4 dilution in most sera tested. Afro-Colombian individuals showed lower activity than other ethnic groups and febrile patients produced stronger inhibition than those without fever. |
| doi_str_mv | 10.4269/ajtmh.2005.73.5_suppl.0730038 |
| format | Article |
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Afro-Colombian individuals showed lower activity than other ethnic groups and febrile patients produced stronger inhibition than those without fever.</description><identifier>ISSN: 0002-9637</identifier><identifier>EISSN: 1476-1645</identifier><identifier>DOI: 10.4269/ajtmh.2005.73.5_suppl.0730038</identifier><identifier>PMID: 16291765</identifier><language>eng</language><publisher>United States: ASTMH</publisher><subject>Adult ; Animals ; Anopheles - parasitology ; Anopheles albimanus ; Antibodies, Protozoan - blood ; Colombia - epidemiology ; Endemic Diseases ; Female ; Humans ; Immune Sera - immunology ; Malaria, Vivax - epidemiology ; Malaria, Vivax - immunology ; Malaria, Vivax - transmission ; Male ; Plasmodium vivax ; Plasmodium vivax - immunology</subject><ispartof>The American journal of tropical medicine and hygiene, 2005-11, Vol.73 (5 suppl), p.38-43</ispartof><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c510t-541681ee155360f85d3ecbfadf832fe285080454604a89b933be74523eb0a3c73</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,781,785,27929,27930</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16291765$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>AREVALO-HERRERA, MYRIAM</creatorcontrib><creatorcontrib>SOLARTE, YEZID</creatorcontrib><creatorcontrib>ZAMORA, FELIPE</creatorcontrib><creatorcontrib>MENDEZ, FABIAN</creatorcontrib><creatorcontrib>YASNOT, MARIA FERNANDA</creatorcontrib><creatorcontrib>ROCHA, LEONARDO</creatorcontrib><creatorcontrib>LONG, CAROLE</creatorcontrib><creatorcontrib>MILLER, LOUIS H</creatorcontrib><creatorcontrib>HERRERA, SOCRATES</creatorcontrib><title>PLASMODIUM VIVAX: TRANSMISSION-BLOCKING IMMUNITY IN A MALARIA-ENDEMIC AREA OF COLOMBIA</title><title>The American journal of tropical medicine and hygiene</title><addtitle>Am J Trop Med Hyg</addtitle><description>Plasmodium vivax transmission-blocking activity was assessed in sera from acutely infected patients from a malaria-endemic area in Colombia. 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Afro-Colombian individuals showed lower activity than other ethnic groups and febrile patients produced stronger inhibition than those without fever.</description><subject>Adult</subject><subject>Animals</subject><subject>Anopheles - parasitology</subject><subject>Anopheles albimanus</subject><subject>Antibodies, Protozoan - blood</subject><subject>Colombia - epidemiology</subject><subject>Endemic Diseases</subject><subject>Female</subject><subject>Humans</subject><subject>Immune Sera - immunology</subject><subject>Malaria, Vivax - epidemiology</subject><subject>Malaria, Vivax - immunology</subject><subject>Malaria, Vivax - transmission</subject><subject>Male</subject><subject>Plasmodium vivax</subject><subject>Plasmodium vivax - immunology</subject><issn>0002-9637</issn><issn>1476-1645</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkctu00AUQEeIioaWX0CzgQWSzZ0Zz8NILKZuWkb4UeUlWI1sZ0xS2SR4EkX8PW5jCXas7ubcc6V7EHpHIIyoiD-Wj4duE1IAHkoWcuuP-30bgmQATL1AExJJERAR8ZdoAgA0iAWTl-i1948ARFFCXqFLImhMpOATtHpI9Twrbs0ywyuz0t8-4cVM5_PMzOemyIObtEi-mvwemyxb5mbxHZsca5zpVM-MDqb57TQzCdazqcbFHU6KtMhujL5GF03ZevdmnFdoeTddJF-CtLg3iU6DmhM4BDwiQhHnCOdMQKP4mrm6asp1oxhtHFUcFEQ8EhCVKq5ixionI06Zq6BktWRX6P3Zu-93v47OH2y39bVr2_Kn2x29FUoNBkr_CxIJkgMhA_j5DNb9zvveNXbfb7uy_20J2KcC9rmAfSpgJbNjATsWGPbfjoeOVefWf7fHlw_AhzOw2f7YnLa9s74r23bAiT2dTv8oB9sfA_SM1A</recordid><startdate>20051101</startdate><enddate>20051101</enddate><creator>AREVALO-HERRERA, MYRIAM</creator><creator>SOLARTE, YEZID</creator><creator>ZAMORA, FELIPE</creator><creator>MENDEZ, FABIAN</creator><creator>YASNOT, MARIA FERNANDA</creator><creator>ROCHA, LEONARDO</creator><creator>LONG, CAROLE</creator><creator>MILLER, LOUIS H</creator><creator>HERRERA, SOCRATES</creator><general>ASTMH</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>C1K</scope><scope>F1W</scope><scope>H97</scope><scope>L.G</scope><scope>M7N</scope><scope>7X8</scope></search><sort><creationdate>20051101</creationdate><title>PLASMODIUM VIVAX: TRANSMISSION-BLOCKING IMMUNITY IN A MALARIA-ENDEMIC AREA OF COLOMBIA</title><author>AREVALO-HERRERA, MYRIAM ; SOLARTE, YEZID ; ZAMORA, FELIPE ; MENDEZ, FABIAN ; YASNOT, MARIA FERNANDA ; ROCHA, LEONARDO ; LONG, CAROLE ; MILLER, LOUIS H ; HERRERA, SOCRATES</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c510t-541681ee155360f85d3ecbfadf832fe285080454604a89b933be74523eb0a3c73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Adult</topic><topic>Animals</topic><topic>Anopheles - parasitology</topic><topic>Anopheles albimanus</topic><topic>Antibodies, Protozoan - blood</topic><topic>Colombia - epidemiology</topic><topic>Endemic Diseases</topic><topic>Female</topic><topic>Humans</topic><topic>Immune Sera - immunology</topic><topic>Malaria, Vivax - epidemiology</topic><topic>Malaria, Vivax - immunology</topic><topic>Malaria, Vivax - transmission</topic><topic>Male</topic><topic>Plasmodium vivax</topic><topic>Plasmodium vivax - immunology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>AREVALO-HERRERA, MYRIAM</creatorcontrib><creatorcontrib>SOLARTE, YEZID</creatorcontrib><creatorcontrib>ZAMORA, FELIPE</creatorcontrib><creatorcontrib>MENDEZ, FABIAN</creatorcontrib><creatorcontrib>YASNOT, MARIA FERNANDA</creatorcontrib><creatorcontrib>ROCHA, LEONARDO</creatorcontrib><creatorcontrib>LONG, CAROLE</creatorcontrib><creatorcontrib>MILLER, LOUIS H</creatorcontrib><creatorcontrib>HERRERA, SOCRATES</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) 3: Aquatic Pollution & Environmental Quality</collection><collection>Aquatic Science & Fisheries Abstracts (ASFA) Professional</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>MEDLINE - Academic</collection><jtitle>The American journal of tropical medicine and hygiene</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>AREVALO-HERRERA, MYRIAM</au><au>SOLARTE, YEZID</au><au>ZAMORA, FELIPE</au><au>MENDEZ, FABIAN</au><au>YASNOT, MARIA FERNANDA</au><au>ROCHA, LEONARDO</au><au>LONG, CAROLE</au><au>MILLER, LOUIS H</au><au>HERRERA, SOCRATES</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>PLASMODIUM VIVAX: TRANSMISSION-BLOCKING IMMUNITY IN A MALARIA-ENDEMIC AREA OF COLOMBIA</atitle><jtitle>The American journal of tropical medicine and hygiene</jtitle><addtitle>Am J Trop Med Hyg</addtitle><date>2005-11-01</date><risdate>2005</risdate><volume>73</volume><issue>5 suppl</issue><spage>38</spage><epage>43</epage><pages>38-43</pages><issn>0002-9637</issn><eissn>1476-1645</eissn><abstract>Plasmodium vivax transmission-blocking activity was assessed in sera from acutely infected patients from a malaria-endemic area in Colombia. 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| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Adult Animals Anopheles - parasitology Anopheles albimanus Antibodies, Protozoan - blood Colombia - epidemiology Endemic Diseases Female Humans Immune Sera - immunology Malaria, Vivax - epidemiology Malaria, Vivax - immunology Malaria, Vivax - transmission Male Plasmodium vivax Plasmodium vivax - immunology |
| title | PLASMODIUM VIVAX: TRANSMISSION-BLOCKING IMMUNITY IN A MALARIA-ENDEMIC AREA OF COLOMBIA |
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